#Macrophage

Prof. Akiko Iwasaki

VirusesImmunity

This is a cautionary tale of how anti-Spike antibody may make COVID disease worse. In this study, the authors show that anti-Spike IgG made SARS-CoV disease worse by switching macrophage

Dr. Harriet Manley

Our new paper jam-packed with exciting lattice #lightsheet microscopy is online! Imaging #zebrafish leukocytes, we reveal new dynamic cellular & subcellular features in vivo. At this resolution, these fast‐moving cells

Michael Kronenberg

SubBasepair_Res

Big part of $TRIL future valuation will be solid tumor data. $ALXO ALX148 in a ph1 trial demonstrated 40% ORR in combo w/ PDL1i for checkpoint inhibitor naive HNSCC tumors.

a new thread related to my last tweet to show you all how pretty the characters from CaW are first, we have white blood cell 10/10 very pretty his smile

We are excited to share ‘Host-viral infection maps reveal signatures of severe COVID-19 patients’ https://www.cell.com/cell/fulltext/S0092-8674(20)30568-7 led by @bost_pierre and @AmirGiladi. Collab with the Zheng Lab from the Shenzhen Third People’s

Benjamin Stewart

A little thread with data incorporating #scRNAseq, #macrophages, #lung, and of course #COVID19 this paper in @SciImmunology identifies populations of lung macrophages in & (though all characterisation in )https://immunology.sciencemag.org/content

Benjamin Stewart

#singlecell #COVID19 paper alertThis one has lots of clues for our understanding of #COVID19 and heavily implicates mononuclear phagocytes as central to severe pathology.A thread....https://www.biorxiv.org/content/10.1101/2020.04.08.029769v1 They sam

Happy Postdoc appreciation week ! To celebrate, we are highlighting our amazing postdocs! A thread: Hit a roadblock with your research? We appreciate @Fiber_matt is always available for an impromptu

Erik Hermstad MD MBA

Vitamin D and COVID-19.I saw @ChrisMasterjohn post something about how he wasn't taking vitamin D because it could potentially increase ACE-2 receptors. So, I started checking it on my admitted

New study by @IdoAmitLab on scRNA-seq in mild (n=3) vs severe (n=6) COVID-19 patient, w/ computational disentangling of cells directly infected by SARS-CoV-2 vs those indirectly impacted. https://www.sciencedirect.com/science/article/pii/S00928674203

a thread of @tongthk as beautiful microscopic things #tongthk #ต๋องเฉยๆ #ปลาน้อยของต๋อง Lysosome in prep bind to mTORC1 protein Chloroplast during the light reaction The Neutrophils, white blood c

1/5 African S. Typhimurium ST313 has 23 Lineage 2-specific pseudogenes, discovered by @DrRobKingsley in 2009, inc ybjZ.But what is function?In collab with Jared Honeycutt @monack_lab, we've discovered that MacB (YbjZ)

Jeroen den Dunnen

Why do #COVID19 patients often become critically ill around 1.5 weeks? Our latest work (now on @biorxivpreprint) may provide an explanation (and therapy) for this: aberrant IgG antibodies. A thread

SARS-CoV-2: A Storm is Raging: Our Preview/Perspective for Chen on JCI: by day 8 after infection, it's cytokine storm and CD4/CD8 decrease that causes respiratory failure, not viral load. Agree

Proposed COVID-19 Pathophysiology [Part 2 of 3]:Enter the magnificent macrophage.What do #COVID-19 and hemophagocytic lymphohistiocytosis (#HLH) potentially have in common?...let’s continue our journey onward into the cytokine storm. First, let’s

1. I came over a report the other day, and then it hit me. This thread will explain what I realized [may] be happening. Disclosures: This is an exploratory thread.