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Proposed COVID-19 Pathophysiology [Part 3 of (now) 4]: Coagulopathy Strikes Back.What happens when #COVID19 clashes with the

Proposed COVID-19 Pathophysiology [Part 2 of 3]:Enter the magnificent macrophage.What do #COVID-19 and hemophagocytic lymphohistiocytosis (#HLH) potentially have in common?...let’s continue our journey onward into the cytokine storm. First, let’s

1. Type III hypersensitivity reactions typically develop ~6 h after exposure to antigen.This is the timeframe we are often seeing patients rapidly decompensate in (2L -> 15L -> intubation), usually

Proposed COVID-19 Pathophysiology [Part 1 of 3]What do #COVID-19 and #Dengue fever potentially have in common?The answers have significant potential clinical implications in COVID-19.Buckle up. It's a long one.Let’s take

A hematology @tony_breu-style tweetorial: Why does lymphopenia occur in #COVID19?A normal WBC count and lymphopenia are seen in patients affected by COVID-19, but why it occurs has bothered me since