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Prof. Akiko Iwasaki
VirusesImmunity
After many months of planning and hard work by so many (incl. @hmkyale @Dianaberrent @wade_schulz @CharleszYaleMed @Aaronmring @DaisySMassey @JeffGehlhausen), today, we are launching our research study to understand how vaccination
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Do some people have cross-reactive antibodies to #SARSCoV2? If so, who are they? And are these cross-reactive Abs protective against #COVID19? A fascinating study by @KevinWNg et al provides answers.
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As we approach the cold winter months in the Northern Hemisphere, I want to share these movies of mucociliary clearance (MCC) in the trachea of mice housed at 10% vs.
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Are you confused about the role of type I interferons (IFN) in #SARS_CoV_2 infection? Here is my speculation on what makes IFN-I helpful vs. harmful in #COVID19 patients - it
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An excellent new study by @BrodinPetter’s team on the differences between MIS-C and Kawasaki disease. This is incredibly timely and informative. Here are a couple of highlights. (1/)https://www.cell.com/cell/fulltext/S0092-8674(20)31157-0
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A 25 yr old patient in Nevada has a confirmed case of #COVID19 reinfection (48 days apart between 1st and 2nd PCR). This time, unlike the case in Hong Kong,
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A first case of #COVID19 reinfection from HKU, with distinct virus genome sequences in 1st and 2nd infection (142 days apart). Kudos to the scientists for this study.This is no
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Very excited to share this work by the heroic team - @carolilucas Pat Wong @sneakyvirus @tiago21bio et al on “Longitudinal analyses reveal immunological misfiring in severe COVID-19”. A thread on
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In some children, #COVID19 takes the form of #KawasakiDisease-like symptoms. So what exactly is #KawasakiDisease? It's an illness caused by inflammation of the blood vessels in children < 5 yrs
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A lot of people are wondering why #Japan has so few cases of #COVID19. In this commentary, @NathanGrubaugh and I speculate on some possible reasons. (1/n)https://www.embopress.org/doi/10.15252/emmm.202012481 An important observation made
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In this new piece, I present "Antidote to toxic principal investigators". We must protect our next generation scientists from the principal investigators who abuse their powers and mistreat their trainees.
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Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlates with severe disease progression. This is a clue that #pyroptosis may be a
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