#Cytokines

Covfefe Shecky Jones,King Of Shade👑aka BROLENE🌊

King_Of_Shade

How COVID-19 kills:A Pathophysiological discussion in lay terms.The Lungs consist of a network of air conduits which subdivide into a finer network of air passages which terminate into air sacs

Prof. Akiko Iwasaki

VirusesImmunity

Very excited to share this work by the heroic team - @carolilucas Pat Wong @sneakyvirus @tiago21bio et al on “Longitudinal analyses reveal immunological misfiring in severe COVID-19”. A thread on

Sunny Shin

SunnyShinLab

Thrilled to share our new @cellhostmicrobe study! We found a central role for the alveolar epithelium in responding to IL-1 from #Legionella-infected alveolar macs by producing GM-CSF, which metabolically reprograms

Learn Nutrition

learnnutrition_

Ketogenic diet: 14 mechanisms of action #Keto1. Lowers blood sugar & insulin levels2. Decreases leptin3. Produces ketone bodies, an alternate source of energy, instead of glucose4. Changes neurotransmitters, GABA, glutamate,

Michael Kronenberg

SubBasepair_Res

Ribas et al. 2020 shows that melanoma PDLi responders have higher levels of pre-treatment HLA gene expr. in bulk tumor RNA relative to non-responders, with the difference being amplified upon

Monox 🍒 🛴📏

Monox5

Parce qu'il n'y a pas que les vaccins dans la vie ...https://www.nytimes.com/interactive/2020/science/coronavirus-drugs-treatments.html Extraits choisis L'HCQ est out le Remdesivir ce n'est guère mieux Les anticorps. .. fau

Lumos Biotech

lumosbio

THREAD from the new #bradykinin research (pre-print) from :"We propose that the severity of the disease and many deaths are due to a local vascular problem due to activation of

Avraham Z. Cooper, MD

AvrahamCooperMD

1/ Ever wonder why eosinophils vanish from the blood after exposure to steroids? I assumed that steroids somehow destroy them and that is why they disappear.But there's a lot more

Spotted Toad

toad_spotted

The simple, accurate, anti-WHO name for the disease is SARS2, full stop. This is not just a political decision. There's a ton of data on SARS1 that's useful to keep

Lucy Bell

LucyCKBell

After a week of self-isolation (with presumed mild COVID ) reading just a few of the astonishing number of #SARSCoV2 & #COVID19 papers/pre-prints in between doses of paracetamol... Some thoughts

Amit Schandillia

Schandillia

[THREAD: HYDROXYCHLOROQUININE]1/24@realDonaldTrump calls it the new magic bullet and extorts it from India. India calls it the magic bullet and pretends to be the savior of humanity. Scientists stand conflicted,

Dr Tarun Deep Singh

tarunds

Lets try and learn some basics of the COVID-19 illnessSo to understand what’s happening you need to understand the story behind it.(A Thread) 80% people will have flu like sicknessMild/Initial

Robert Plenge

rplenge

Another week and more data on the immune response to SARS-CoV2 and the disease it causes, COVID-19. This information is critical for therapeutic repurposing. A short thread on interferon and

Joshua C. Doloff

DoloffLab

OMG. Who sent this thing, The Terminator?! (Work just published in @NatureMedicine shows antibody levels decline quickly in 2-3 months across both symptomatic and asymptomatic patients.)https://www.reuters.com/article/us-health-coronavirus-

Nick Mark MD

nickmmark

Interesting preprint of the #LIVEAIR study of #lenzilumab in #COVID19:-double blind RCT n=502 hospitalized pts on suppl O2-lenzilumab associated with improved survival w/o ventilation: 84% vs 77.9% -larger benefit when

Dr. Arinjay Banerjee

sci_questions

Our latest study to understand the dynamic regulation of #interferon (#IFN) and #SARSCoV2 infection. summarizing what we found and what needs to be done to understand the dynamic interplay of