2/x Con’t quote,

“platelets hyperactivated in C19 subjects presenting nonsevere & severe symptoms,
with AGGREGATION occurring at suboptimal #thrombin concentrations

...platelets adhered more efficiently...

Platelets may...contribute to overwhelming THROMBO-INFLAMMATION in C19”
3/ Quoting

“[platelets] are an important source of inflammatory mediators.
While a LOWER PLATELET COUNT is associated with severity/mortality, little is known about platelet function during C19.”

What causes LOWER platelet count
and platelet AGGREGATION
in some C19 patients?
4/x Interestingly, can the SAME question be asked for some people with severe adverse reactions,
post-Covid19 VACCINE,
-LOWER platelet count

aka vaccine induced immune thrombotic thrombocytopenia (VITT)? https://www.bmj.com/content/373/bmj.n954
6/x Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19

8/ “The isolated [SARSCoV2 spike]

Platelet activation

When whole blood was exposed to SPIKE PROTEINS
even at low concentrations,
erythrocytes showed AGGLUTINATION,
with membrane spreading
and formation of platelet-derived microparticles”
9/x Con’t

“In all samples, spontaneous amyloid deposits formed after exposure to the SPIKE PROTEIN *without* need for thrombin exposure


..SPIKE S1 not only interacts directly with BOTH
and with..fibrinogen and.. fibrin,
...alter the way blood clots.”

*When SPIKES and thrombin were added to HEALTHY PPP*,
formation of abnormal amyloid deposits INCREASED.

These also showed significant changes in the blood cells' ultrastructure, including the red cells and platelets.”

“..extensive spontaneous fibrin networks following ADDITION of SPIKE PROTEIN to whole blood
the ultrastructural appearance seen on COVID19-positive blood smears.

..primary features were
anomalous CLOTTING
amyloid in the CLOTS
spontaneous fibrin network formation”
12/x Con’t quoting

“it [ie spike protein] may alter blood flow in COVID19.
The microfluidics simulation showed that the PPP from COVID-19 patients, which is almost pure fibrinogen,

"We suggest that, in part,...” >
13/x Con’t quoting

“THE PRESENCE OF SPIKE PROTEIN in [blood] circulation may contribute to the
AND may cause severe impairment of fibrinolysis.
Such lytic impairment may be the direct cause of the LARGE MICROCLOTS we have noted here”
I wonder whether the Covid19 vax-induced SARSCOV2 spike protein can exert similar effects in some people who suffer vaccine induced immune thrombotic thrombocytopenia (VITT),
given that vax-induced spike protein is identical to that in SARSCOV2 that causes Covid19?
16/x Another great article by Dr @sebrushworth

Is the Astra-Zeneca vaccine killing people?

17/x SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia


„... cases of immune #thrombocytopenia and BLEEDING without thrombosis that were induced or revealed after ... mRNA... vaccines produced by Moderna ...and Pfizer ...reported“ https://www.nejm.org/doi/full/10.1056/NEJMe2106315
17.1/x Con’t Quoting

„39 persons with.. #thrombosis and #thrombocytopenia ... 5 to 24 days AFTER initial vaccination with ... #AstraZeneca,
a recombinant #chimpanzee adenoviral vector encoding SPIKE PROTEIN..
HEALTHY or in medically stable condition..
Most..were women <50 years“
17.2/x Con’t Quoting

„A remarkably high % of patients had #thromboses at unusual sites — specifically, CEREBRAL VENOUS SINUS THROMBOSIS or THROMBOSIS in portal, splanchnic, or hepatic veins.

17.3/x Con’t quoting

„The median platelet counts at diagnosis were ~20,000 to 30,000 per cubic millimeter (range, ~10,000 to 110,000)...

High levels of d-dimers and low levels of fibrinogen were common and suggest SYSTEMIC activation of COAGULATION.

~40% of the patients DIED“
17.4/x Con’t quoting

„some [DIED] from
-ischemic brain injury
-superimposed hemorrhage,
-both conditions, often after anticoagulation.

... the pathogenesis of this syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) is not yet clear...“
17.5/ Con’t quote

„169 [cases] cerebral venous sinus #thrombosis
53 [cases] splanchnic vein #thrombosis...[AstraZeneca]

35 [cases] CNS #thrombosis ...Pfizer..

5 [cases] cerebral venous sinus #thrombosis...Moderna..

...these numbers may be #underestimates..reporting voluntary“
17.7/x Quoting more

„In almost every patient, HIGH levels of antibodies to platelet factor 4 ( #PF4)–polyanion complexes were identified ...“

This is interesting because ... >
Quoting Results,

„6 critically ill COVID‐19 samples demonstrated significant platelet activation in the ABSENCE OF HEPARIN ...
All 6 platelet‐activating samples contained
**IgG‐specific antibodies against [receptor binding domain], SPIKE [protein], or both proteins...**„
17.10/x Con’t quoting

„A subset of critically ill COVID‐19 patient sera thus contains ICs [immune complexes] that mediate platelet activation via FcγRIIA signalling
The lack of anti‐PF4/heparin antibodies and presence of heparin‐INDEPENDENT serotonin release assay activation“
17.11/x Con’t

„...strongly RULES OUT heparin-induced thrombocytopenia
certain critically ill COVID‐19 patients feature a novel IC [immune complex]-mediated THROMBOTIC MICROANGIOPATHY ..SIGNIFICANT PLATELET ACTIVATION.
..highly #prothrombotic
..with unique platelet‐activating“
As noted in 17.9/x above,

„All 6 platelet‐activating samples [from 6 critically ill, NON-vaccinated C19 patients] contained
*IgG‐specific antibodies AGAINST:

- the receptor binding domain
- BOTH proteins of the SARSCOV2 virus.*„
To repeat from 17.11/x,

„These 6 critically ill, NON-vaccinated COVID‐19 patients feature a novel immune complex-mediated THROMBOTIC MICROANGIOPATHY [with] SIGNIFICANT PLATELET ACTIVATION.
..highly #prothrombotic
..with unique platelet‐activating...“

The $64 Question:

How is this any different from the observed adverse effects of #AstraZeneca and other SARSCOV2 spike protein-inducing experimental mRNA/DNA vaccines?????
18/x The point i am trying to make:

-severe Covid symptoms in certain critically-ill, *unvaccinated* C19 patients (whose symptoms arise for complex reasons - NOT just Covid)

s/be compared and contrasted with

-severe adverse effects that arise in some healthy people, post-vax >
18.1/x Thus, questions s/be asked:

Were it not for vaccine, would many young, healthy people who suffered adverse effects, post-vax, STILL have suffered THESE SAME adverse effects as those suffered by critically-ill, unvaccinated Covid19 patients?? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266166/

What is common denominator between 1st group (likely, with comorbidities) and 2nd?

Could immune system of vax‘d ppl react
due to partial #homology between vax-induced spike and certain human molecules (self)?

If so, could #molecularmimicry trigger autoimmune disease?
18.4/x An example of molecular mimicry
👇 https://twitter.com/My2puppies1/status/1384377949890088960?s=20
19.1/ Before looking at above, let’s look here

#MolecularMimicry between SARSCoV2 SPIKE glycoprotein and mammalian PROTEOMES:
implications for vax


„..MASSIVE heptapeptide SHARING exists between:
- SARSCoV2 spike glycoprotein
- human proteins“ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499017/#!po=1.78571
19.2/x con‘t quoting

and HIGHLY #IMPROBABLE from a mathematical point of view...

This study thoroughly quantifies the ... peptide SHARING of SARS-CoV-2 spike glycoprotein-
a major antigen of the virus-
with mammalian proteomes.“
19.3/x con’t

„MASSIVE peptide COMMONALITY is present with HUMANS ... that undergo pathologic consequences following SARSCoV2 infection.
... INDISPUTABLE PROOF IN FAVOR OF #MolecularMimicry as a potential mechanism that can contribute to or cause SARSCoV2 associated diseases.“
Q: Given that MASSIVE peptide commonality exists, how can one be 100% certain that PCR test will ONLY confirm presence of SARSCOV2 spike protein,
and NOT the presence of aforementioned human proteins for which MASSIVE heptapeptide SHARING exists due to #MolecularMimicry?
19.5/x Here:

„SARSCoV2 RNA reverse-transcribed and integrated into human genome

„...*SARSCoV2 RNAs* can be reverse-transcribed and integrated into the human genome and that transcription of the integrated sequences
MIGHT ACCOUNT FOR PCR-POSITIVE TESTS.“ https://pubmed.ncbi.nlm.nih.gov/33330870/ 
19.6/x Con‘t quote

„This..may explain why patients can continue to produce viral *RNA* [LONG] AFTER RECOVERY..“

NB Viral *RNA* does *NOT* equate to actual virus!

Given that these particular PCR-POSITIVE TESTS DO NOT pertain to infectious or presymp people, they are NOT „CASES“
20/x More on #molecularmimicry

Potential antigenic cross-reactivity between SARSCoV2 and human tissue ..possible link to an INCREASE in #autoimmune diseases

„ we tested 5 different blood specimens that were..positive for SARSCoV2 IgG and IgM antibodies“ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246018/

-anti-nuclear antibody (ANA)
-anti-extractable nuclear antigen (ENA)
-anti-double-stranded DNA (dsDNA)
-actin antibody
-mitochondrial antibody
-rheumatoid factor (RF)
-C1q immune complexes.

..surprised to find 3 of 5 specimens had significant ELEVATIONS in“

„- ANA
- actin
- mitochondrial antibodies
but not against dsDNA or RF.

[Are there] patterns of #cross-reactivity between SARS-CoV-2 and autoimmune target proteins[?]

Vaccine-induced autoimmunity from autoimmune cross-reactivity is associated with: „
20.3/x Quoting

-Guillain-Barré syndrome
-demyelinating neuropathies
-systemic lupus erythematosus
-postural orthostatic tachycardia syndrome
in susceptible subgroups..

we studied relationships between SPIKE and nuclear PROTEINS...and autoimmune target proteins“
20.4/x Quote

„The virus can in fact affect the body from head to toe including
- nervous
- cardiovascular
- immune
- digestive systems

Is it possible that some of extensive organ, tissue, and cellular damage done by SARSCoV2 is due to VIRAL ANTIGENIC MIMICRY with human tissue“


IF (quoting) „some of extensive organ, tissue, and cellular damage done by SARSCoV2 is due to VIRAL ANTIGENIC MIMICRY with human tissue“,

wouldn‘t it be in the realms of possibility that the VACCINE-INDUCED Spike Protein would ALSO induce the aforementioned?
20.6/x Con’t

“..the SARS-CoV-2 SPIKE glycoprotein
lung surfactant proteins
SHARED 13 out of 24 pentapeptides..

immune response following infection with SARS-CoV-2 may lead to
pulmonary surfactant proteins,
followed by SARS-CoV-2-associated lung disease”

“they warned AGAINST the use of the ENTIRE SARS-CoV-2 ANTIGENS [eg mRNA for SPIKE PROTEIN] in the vaccines...

we feel that our own findings that 21 of 50 tissue antigens had moderate to strong REACTIONS with SARS-CoV-2 antibodies are a sufficiently strong indication of”
“strong indication of CROSS-REACTION between
- SARS-CoV-2 proteins [eg SPIKE]
- a variety of tissue antigens beyond just pulmonary tissue
which could lead to autoimmunity against
- connective tissue
- cardiovascular system
- gastrointestinal system
- nervous system.”
20.9/x Con’t quoting

“We must consider that finding a vaccine for a disease may normally take YEARS [!!].
There are reasons for all the precautions involved in developing a vaccine, not the least of which are UNWANTED side-effects.
In light of information discussed above ..” >
20.10/x Con’t quoting

“about the CROSS-REACTIVITY of the SARS-CoV-2 proteins [eg SPIKE]
human tissues
the possibility of either:
- inducing autoimmunity,
- exacerbating already unhealthy conditions, or
- otherwise resulting in unforeseen consequences, ..”

“it would only be PRUDENT TO DO MORE EXTENSIVE RESEARCH regarding the autoimmune-inducing capacity of the SARS-CoV-2 antigens [including the SPIKE].

The promotion and implementation of such an ***AGGRESSIVE “immune passport” program worldwide***

in the ABSENCE of..”
20.12/x Con’t quoting

“..in ABSENCE of thorough and meticulous safety studies may exact a MONUMENTAL COST ON HUMANITY in the form of ANOTHER epidemic,
this time a rising tide of INCREASED #autoimmune diseases and YEARS OF SUFFERING that come with them”
👇 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246018/
Re-quoting 20.7/x & 20.8/x

“...our own findings that 21 of 50 tissue antigens had moderate to strong REACTIONS with SARS-CoV-2 antibodies are a sufficiently strong indication of CROSS-REACTION between
- SARS-CoV-2 proteins [eg SPIKE]
- a VARIETY of tissue antigens..”
Due to this aforementioned *CROSS-REACTIVITY*,
how can one be 100% certain that PCR test ALSO does NOT (inadvertently) test positive for the presence of one or more of these aforementioned TISSUE ANTIGENS
(in addition to, or instead of, the SARSCOV2 Spike Protein)?

• [~1/3] of the potentially targeted human proteins (putative autoantigens) are KEY PLAYERS IN THE ADAPTIVE IMMUNE SYSTEM

• The list of viral/human protein matches provides CLUES on which (parts of) #epitopes might be involved in the immunopathogenesis of COVID-19...“

• ..indicates which #epitopes might be responsible for #autoimmunological #PathogenicPriming ..following exposure to SARS-CoV-2 or relatives FOLLOWING vax

• These #epitopes SHOULD BE EXCLUDED from #vaccines ...to MINIMISE autoimmunity due to RISK of pathogenic priming“

„HOMOLOGY between:
• HUMAN [proteins]
• VIRAL proteins
is an established factor in viral- [natural-] or vaccine-induced autoimmunity. ..

Immunogenic peptides in viruses or bacteria that MATCH human proteins are good candidates for pathogenic priming peptides ..“
21.4/x Quoting

„SAR-CoV-2 SPIKE proteins ... immunogenic #epitopes in each SARS-CoV-2 protein were compared to HUMAN proteins -
in search of HIGH local #homologous matching.

ONLY ONE immunogenic epitope in a SARS-CoV-2 had NO homology to human proteins.“
21.5/x Quoting

„Mapping of the genes encoding human protein ...point to targets that could explain ...[C19] symptoms..
SARS-CoV-2 virus has numerous OTHER proteins and polyproteins,
each which may serve as an ANTIGEN SOURCE during infection
leading to #autoimmunity.“
21.6/x Quoting


37 SARS-CoV-2 proteins were downloaded from the NCBI SARS-CoV-2 NCBI resource.
Of these, 8 proteins had no recognizably immunogenic peptides.
The remaining [29] proteins had [1 to 6] immunogenic peptides (Table 1).“

„The proteins with the largest number of immunogenic peptides were the Spike,
or S protein (N ​= ​6 in total),
All of the [SARSCOV2 proteins; ie immunogenic #epitopes] had at least ONE MATCH to human proteins -
except one..“

„Remarkably, over 1/3 (11/27) of immunogenic proteins in SARS-CoV-2 have potentially PROBLEMATIC HOMOLOGY to proteins that are key to the human #adaptive immune system (emboldened in Table 1)

SARS-CoV-2 [including vax-induced SPIKE] could impair immune response, at first“

„and then, over time, the immune system could begin to mount an attack on myriad of [human] proteins.

Most of..human target proteins had low overall homology but HIGH LOCAL HOMOLOGY OVER SHORT SEGMENTS OF THEIR EPITOPES.

.. numerous proteins expressed in [human] tissues“
23/x Let‘s look at this paper https://twitter.com/SabinaWalker18/status/1384454468314419204?s=20
23.2/x Cont quote

„[If yes, could] #MolecularMimicry between...viral proteins [including SPIKE protein] and human tissues ... be the cause[?]“

Remember that ANTIBODIES may arise:
• after natural infection
• after mRNA/DNA vax that induces the SARSCOV2 SPIKE protein
23.3/x Con‘t quoting,

„We applied both:

• human MONOCLONAL anti-SARSCov2 antibodies (SPIKE protein, nucleoprotein)
• rabbit polyclonal anti-SARSCov2 antibodies (envelope protein, membrane protein)

to 55 different TISSUE ANTIGENS.“
23.4/x Con‘t quoting,

„...SARSCoV2 antibodies had #reactions with 28 [TWENTY-EIGHT!!] out of 55 tissue antigens

representing ...tissue groups that included:
•barrier proteins
•neural tissues
and more.“
„..selective epitope mapping using BLAST..
showed SIMILARITIES & #HOMOLOGY between SPIKE, nucleoprotein..
HUMAN tissue antigens:
• mitochondria M2
• F-actin
• TPO [thyroid peroxidase]

..extensive IMMUNE #CrossReactivity between..ANTIBODIES and different ANTIGENS“ >
23.6/ Quote

„[This IMMUNE #CrossReactivity] may:
• [affect] multi-system disease process of C19
• INFLUENCE #severity of disease
• PRECIPITATE onset of #autoimmunity in susceptible subgroups
• ...exacerbate autoimmunity in subjects that have PRE-EXISTING #AutoimmuneDiseases
23.7/x Con’t quoting

„..human monoclonal antibodies used are ... almost identical with [those recently approved for C19 patients].

Thus, our results can establish the potential risk for #autoimmunity and multi-system disorders with COVID-19 ...“ >
23.8/x Con‘t quoting

„that may come from #CrossReactivity between:

and thus ensure that ... [experimental mRNA/DNA] vaccines ... are truly safe to use against [Covid19].“
23.9/x Con‘t quoting


... IMMUNOLOGISTS who focus on AUTOIMMUNITY have been concerned whether:
• infection
• a newly developed [experimental mRNA/DNA] vaccine itself

can trigger #autoimmunity via #CrossReactivity.“
23.10/ Quoting

#CrossReactivity occurs when..sequence #HOMOLOGY exists between:
• a PATHOGEN [eg vax-induced SARSCOV2 SPIKE]
• SELF-TISSUE [HUMAN] proteins.

...antibodies formed against SARSCoV2 would ALSO BIND TO HUMAN TISSUE proteins
leading to #autoimmune REACTIVITY.“
23.11/x Con’t quoting

„An insufficiently vetted [experimental mRNA/DNA] vaccine might mean
trading freedom from COVID-19
to an AUTOIMMUNE ASSAULT in the future.“
23.12/x Quote

„.. 3 Q’s regarding role of #CrossReactivity with SARSCoV2:

1) Does #CrossReactivity [▶️] multi-system disorders...?
2) How does #CrossReactivity contribute to..SARSCoV2–induced #autoimmunity?
3) .. #autoimmune developmt with infection
23.13/x Quoting

„...the issue of peptide SHARING between SARSCoV2 SPIKE glycoprotein and #LUNG_Surfactant proteins:

...because SARSCoV2 and #LUNG_Surfactant proteins SHARED 13 [THIRTEEN!!] of 24 pentapeptides,
the immune response following infection..[or vax-induced SPIKE]..“ >
„may lead to #CrossReactions with pulmonary #surfactant proteins,
followed by [C19] lung disease

...indisputable proof of #molecularmimicry as potential mechanism for contributing to [C19] diseases

23.15/x Quoting

„cautioned that..the use of ONLY UNIQUE PEPTIDES
would be most effective way to fight [C19].

Due to SIGNIFICANT RED FLAGS 🚩 for potential #CrossReactivity between SARSCoV2 and HUMAN TISSUE,..
[we studied] interaction of ANTIBODIES made against SARSCoV2 SPIKE..“
23.16/x Quoting

„... with various #autoimmune target proteins associated with many serious diseases.

..we can establish the potential risk for #autoimmunity and multi-system disorders with C19
that may come from #CrossReactivity between OUR OWN HUMAN TISSUES and [SARSCOV2]...“

..SARSCoV2 antibodies reacted from low to very high with 28 of 55 [HUMAN] tissue antigens...[including]:
• gut & barrier proteins
• gastrointestinal system cells
• thyroid
• nervous system
• heart
• joint
• skin
• muscle
• mitochondria
• liver
23.18/x Quoting

„and antigens used for the screening of #autoimmune diseases.
HUMAN anti-SARSCov2 SPIKE protein antibody reacted:
• STRONGEST with neurofilament protein or NFP
• followed by STRONG reactions with M2, GAD-65, and nuclear antigen or NA“

„The reaction of SPIKE protein antibody with TPO [thyroid peroxidase]
and liver microsome was moderate.
Table 1 - SPIKE protein antibody exhibited SIGNIFICANT reactions with 25 of 55 tested target proteins,
with the STRONGEST reactions coming from NFP and M2 antigens“
23.19/x Quoting


>7,000 peer-reviewed studies published on #molecularmimicry and #autoimmune diseases
and >50 recognized #crossreactive relationships between specific viral pathogens and HUMAN tissue proteins [prior to 2020] (1, 4, 8, 14–20).“
#molecularmimicry between SARSCoV2 and HUMAN proteins
..connection between #mimicry and multi-organ disorders

immune response against viral ANTIGENS following infection OR VACCINATION can #crossreact with HUMAN TISSUE antigens that SHARE sequence HOMOLOGY with[eg SPIKE]“
23.21/x Quoting

„resulting in #autoimmune_reactivity,

possibly followed by OUTRIGHT AUTOIMMUNE DISEASE (5, 10, 19, 24, 25).

Some support for this proposed mechanism for induction of #autoimmunity was presented

...compared #immunogenic EPITOPES of SARSCoV2
HUMAN proteins“

„found a HIGH degree of HOMOLOGY with..[including]:
• heart muscle
• skeletal muscle
• thyroid gland
• kidney
• brain
• pituitary gland
• testes
• lung
• GI tract
• eye
• liver
• bone marrow
• adipose tissue
• skin
and many ubiquitous proteins (5).“

„...key target human tissue proteins known to be involved BOTH with:
• extra-pulmonary manifestations of C19
• common #autoimmune diseases.

..we studied:
• alpha-myosin [in heart muscle]
• actin [in skeletal muscle]
• TPO [thyroid peroxidase, in thyroid gland]“
23.24/x Quoting

„Lyons-Weiler studied:
• brain
• liver
• GI tract
• skin

whereas we examined SARSCoV2 #crossreactivity with:
• brain tissue ANTIGENS (MBP, NFP, amyloid-beta, alpha-synuclein, synapsin, tTG-6)
• liver microsomal peptide
• M2 protein
• PDH peptide... „ >
23.25/x Quoting

„ • skin antigens (tTG-2, tTG-3, epithelial cell antigens)

...many other tissue antigens [examined], such as barrier proteins..

...[does] human monoclonal antibody that mimics natural antibodies...react to various HUMAN TISSUE antigens[?]“
23.26/x Quoting

„This immune reaction may be responsible for the multi-organ system disorder [in] severe C19.
Our present study used human #monoclonal_antibodies against SARSCoV2 proteins [including SPIKE], and we found reactivity with 28 out of 55 tested human antigens ..“
23.27/x Quoting

„This #crossreactivity with so many [HUMAN] ANTIGENS raises important CLINICAL CONCERNS.

3) understanding the relationship of SARSCoV2 [including vax-induced SPIKE]
can help predict potential ADVERSE REACTIONS from ..experimental vaccine..use“
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