#Prothrombotic

Coagulopathy twitter! Lots of interest in this, as lots of anecdotal evidence of prothrombotic state.Would urge caution though - for now, outside of a trial, make sure all are on

Menaka Pai, MSc MD FRCPC

So you read today’s NACI advice - AZ ok if you’re 30+! Unless you can wait for mRNA ! And then you read the MANY hot takes from experts, non-experts,

Summary of a hypothesis for Sars-Cov-2:We now suspect that viral proteins attack the B1 subunit of hgb. This may effectively deactivate this subunit. If the virus does this to 100%

so today's webinar is from the ISTH on coagulopathy in #COVID19 A very elevated d-dimer is seen in non-survivors from chinese data#covid19 Like DIC but not quitea microangiopathy?#covid19 #COVID19 is

Why am I now opposed to any further AstraZeneca vaccine being used in Canada? I want to walk you through the math we have available.First, I am using some risk-benefit

Menaka Pai, MSc MD FRCPC

Okay one more thread before bed! Lots of Qs asking "what IS VITT?" Before I get to that, if you'd like an AWESOME metaphor about vaccine choice, please read my

Menaka Pai, MSc MD FRCPC

LONG week on call @HamHealthSci. Lots of calls about #VITT post AZ vaccine. I'm transparent w my patients - I believe empowerment leads to earlier detection, better outcomes, less stress.

Buku Haematology 🅰️➕

BukuHaematology

1/ Antidote news! There has been promise recently regarding antidotes being developed for DOACs. Before we get onto that, a quick summary of what we have so far... 2/ In

Proposed COVID-19 Pathophysiology [Part 3 of (now) 4]: Coagulopathy Strikes Back.What happens when #COVID19 clashes with the

Proposed COVID-19 Pathophysiology [Part 1 of 3]What do #COVID-19 and #Dengue fever potentially have in common?The answers have significant potential clinical implications in COVID-19.Buckle up. It's a long one.Let’s take

Kai Kupferschmidt

Like everything in this pandemic the science around the rare clotting disorder seen in AstraZeneca vaccinees has moved at an incredible pace. As the link has become clear, hints for

Sabina Walker 😀 Master Appl Science (Neuroscience

1/x Platelets Can Associate With SARSCoV2 RNA and Are Hyperactivated in C19 (17/9/2020)Quoting,“...HYPERCOAGULATION and THROMBOSIS contribute to lethality of [C19].Platelets are chiefly implicated in thrombosis.[platelets] CAN interact wi

Gretchen Winter, MD 🌼

At the request of several people, here is a thread on acute liver failure and decompensated cirrhosis in the ICU. Disclaimer: This is a broad overview of some key issues,

The impact of the first companies getting #FDA emergency use authorization & unblinding studies expected to be among the topics debated over at today's #FDA #VRBPAC My Oct 20 story: