#Thrombocytopenia

Rajeev Jayadevan

RajeevJayadevan

Adenovirus-induced thrombocytopenia: the role of von Willebrand factor | Blood | Othman et al American Society of Hematology 2007 |1. Adenoviruses, when given intravenously as in gene therapy, may directly

Menaka Pai, MSc MD FRCPC

Okay one more thread before bed! Lots of Qs asking "what IS VITT?" Before I get to that, if you'd like an AWESOME metaphor about vaccine choice, please read my

Why am I now opposed to any further AstraZeneca vaccine being used in Canada? I want to walk you through the math we have available.First, I am using some risk-benefit

Danielle Maracaja, MD, MHS

Hi, let’s discuss #ITP! Pls respond the poll and see the thread below. #bloodbank #blooducation How comfortable you feel with a platelet of 1 thou/uL in a case of ITP.

1.) It's not just "6 people" that have developed the coagulation disorder from the J&J and AZ vaccines. It's many thousands more.2.) The morderna and pfizer vaccine have WAY more

Menaka Pai, MSc MD FRCPC

LONG week on call @HamHealthSci. Lots of calls about #VITT post AZ vaccine. I'm transparent w my patients - I believe empowerment leads to earlier detection, better outcomes, less stress.

Jeremy Faust MD MS (ER physician)

Two highly concerning papers now live in the New England Journal of Medicine regarding the adenovirus-based AstraZeneca/Oxford vaccine.A small number of patients appear to have had serious clotting events with

Darren Markland

Everyone keeps telling you that the side effects from AstraZeneca and Jansen vaccines are rare and you should get the vaccine. I totally 100% agree with this, but trust is

The intensivist

My observations1. Tachycardia and thrombocytopenia in OPD is a bad sign. 2. Obese and diabetic can worsen any time in second week even if CT on 6th day has low

Yes, the AstraZeneca vaccine-thrombosis association is causal.The temporal relationship is strong, it’s not seen with mRNA vaccines, and there’s a plausible mechanism analogous to heparin-induced thrombocytopenia (HIT)https://www.nejm.o

NEJM with a well performed and convincing study associating the (extremely) rare clotting syndrome seen with the AZ vaccine with development of platelet factor 4 antibodies and a HIT-like syndrome.https://www.nejm.org/doi/full/10.1056/NEJMo

Plain English thread on how VITT might work, according to the latest Greinacher findings https://www.researchsquare.com/article/rs-440461/v1. One of your immune system's jobs is to deal with infections like colds and flus.

Vincent Rajkumar

Astra Zeneca vaccine & blood clots. Summary.Rare form of blood clots plus low platelets. ~60% involve veins of brain. Almost all after 1st dose. Risk (UK MHRA): 1 in 250,000

Pradheep J. Shanker

The JNJ vaccine cases (six of them in total) all occurred in immediate aftermath of taking the vaccine, so if you took the vaccine and are fine, you are safe.

Alex Haagaard (they/them)

[vaccine talk]I’ve got the exact blood disorder that seems to increase risk for a clotting complication with the AZ and J&J vaccines.I’ve also had to decline medical procedures before, when

فاطمة خداده

سلسلة سريعة لتوضيح معنى مرض الHIT أو نقص الصفائح الناتج من الهيبارين وعلاقته بالتجلط و تطعيم الأسترازنكا ١\١٦ أولا الدم يتكون من ثلا