#Preprint

Pramesh CS

cspramesh

I can't believe the @US_FDA Commissioner @SteveFDA announced that 35 out of 100 patients treated with #ConvalescentPlasma will benefit from it. This demonstrates either a lack of understanding of basic

☠️ Duygu Uygun-Tunc ☠️

uygun_tunc

New preprint! " Replication Under Underdetermination: Introducing Systematic Replications Framework" w/ @tunc_necip. In this paper we discuss a core epistemic problem of hypothesis-testing wrt replication studies and offer a replication

Eric Meyerowitz, MD

EricMeyerowitz

1/ I'm going to try to contain myself, but very important/elegant article out tonight in Cell with potentially critical implications for immunity as well as a possible explanation for differential

Alison Lynn Hill

alison_l_hill

New preprint out with @AnjalikaNande +@michaelzlevy + B. Adlam + J. Sheen: We dig into understanding how both the clinical course and transmission network structure of COVID-19 influence the epidemic

Marcio S Bittencourt

MBittencourtMD

This is to my international colleagues that know some of the authors of the terrible observational studies of "drugs to treat COVID-19". Where you are you probably have no idea

Katie Kroeper

KatieKroeper

New paper out today at #JPSP. Across 4 experiments, we investigated how women (and men) perceive tech companies that #counterfeit their gender diversity—by this, we mean companies that exaggerate gender

Ryan Radecki, MD MS

emlitofnote

I've seen a lot of irritation and frustration for @NEJM and their publication of an uncontrolled case series of #covid19 patients treated with #remdesivir – saying, "great, where's the RCT"?Well,

irena papst 😷

irenapapst

we know #COVID19 severity depends on age, but we mostly see the ages of those dying… what about serious, but non-fatal, outcomes like hospitalization? ICU admission? intubation? ventilator use? how

Kristen K. Coleman

drkristenkc

What happens when your "high standard of proof" is so high that it cannot be reached in a reasonable amount of time before implementing common sense infection prevention strategies for

ice9

__ice9

GS-441524 is substantially less toxic than remdesivir, far easier to synthesize, more soluble, and has essentially identical effects because remdesivir is apparently metabolized into it (in spite of having been

Stefan Holderbach

SHolderbach

Time to end the week with a thread on our recent @ChemRxiv preprint from @HITStudies:https://doi.org/10.26434/chemrxiv.12636704.v11/If you want fast protein-ligand binding predictions, without using full docking, can we get away with

Fabian Neumann

fneum_

Providing just a single least-cost solution underplays an immense degree of freedom when planning future energy systems.There are many near-optimal alternatives with attractive properties like social acceptance due to less

Trevor Bedford

trvrb

On Feb 29, using the genetic sequence of the first community case of #COVID19 in Washington State, I made the claim that the Washington State outbreak descended directly from the

Adi Millman

AdiMillman

Happy to share our new preprint about how we solved the mystery of some of the coolest bacterial elements:Retrons function as anti-phage defense systems!https://biorxiv.org/cgi/content/short/2020.06.21.156273v1See thread below by the 3 of

John Cherian

jjcherian

I've seen a lot of news about the LA study, and the error bars of that study may be seriously flawed as well. It is plausible that the data in

Michael Hoffman

michaelhoffman

1/Now in @nature: our Matters Arising letter describing how the @GoogleHealth study claiming an AI system can outperform radiologists at predicting cancer violates basic scientific standards of transparency and reproducibility.