#Interferon

Bruno Filardi, MD, PhD

mab_sp125

Covid-19 e a BCGA epidemia em nosso país, felizmente, até agora não se mostrou com a mesma força que em outros países. Além dos mais lógicos (pirâmide etária, densidade demográfica,

Viral Glycoproteins Group, TPI

vGlycoproteins

#MicroBio21 kicks off today! A few members of the VGP group will be presenting talks and posters (details below), and the programme as a whole looks awesome! Looks to be

Dr. Arinjay Banerjee

sci_questions

Our latest study to understand the dynamic regulation of #interferon (#IFN) and #SARSCoV2 infection. summarizing what we found and what needs to be done to understand the dynamic interplay of

Daniel De Carvalho

decarvalho_lab

Our manuscript ‘Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency’ is out today @nature. Congratulations to first authors @Pari_Mehdipour @sajidMarhon and @IliasEttayebi for this amazing work!https://www.na

Bertrand Delsuc

BertrandBio

Trial negative for all 4 tested interventions (HCQ, remdesivir, inferferon, lopinavir) but the reports terribly lacks granularity Repurposed antiviral drugs for #COVID19; interim WHO SOLIDARITY trial results https://www.medrxiv.org/content/

Samuel Brown

DrSamuelBrown

For clarity, what do we know about treatment of COVID19 (recognizing that knowledge is a spectrum here)? Here's a list (with appropriate caveats) of what we can credibly claim to

Patrick Hsu

pdhsu

The best coronavirus/SARS-CoV-2 biology lecture I have seen so far, by Britt Glaunsinger @UCBerkeley @berkeleyMCB @HHMINEWS @igisci. Covers where it comes from, how it gets into the cell, replicates in

MacKenzie

Smackenziekerr

@PaulGreeff @Smackenziekerr A large volume of evidence come out of hospitals showing that the COVID-19 virus has two stages to the infection of the body.In the first phase, the virus

Dr. Adams Waldorf

uwdrwaldorf

Can a #COVID19 infection during pregnancy lead to infection of the fetus?A mix of suspicious case reports and scientifically inaccurate articles have muddled this area.Actually, SARS-CoV-2 doesn’t even need to

Vagus

hanta_virus_7

Following a rigorous review and data synthesis, the panel agreed on seven treatment recommendations. They note that in their recommendations, the word "recommend" indicates strong recommendations, and the word "suggest"

Peter Kolchinsky

PeterKolchinsky

3) But damn if some viruses aren’t smarter still. For example, the herpes virus called cytomegalovirus (sounds like a virus from Cybertron) produces a decoy MHC pedestal that cons NK

Paul Bleicher

pbleic

1/ Basics (for non-immunologists) of important new results in COVID-19 immunity. The new finding helps explain how our immune system responds to COVID-19, perhaps why men are more prone to

Anand Patel

Anand_88_Patel

It has been an incredible month for new research about MPNs and MPN-AP/BP! Here are some articles that caught my eye (by no means a comprehensive list!) #mpnsm #leusm A

Lumos Biotech

lumosbio

"Imbalanced host response to #SARSCoV2 drives development of #COVID19" Highlighting "We propose that reduced innate #antiviral defenses coupled with exuberant inflammatory #cytokine production are the defining and driving feature

Anjill 🕊

AnjillofLight_

1. I came over a report the other day, and then it hit me. This thread will explain what I realized [may] be happening. Disclosures: This is an exploratory thread.

Dr. Angela Rasmussen

angie_rasmussen

Check out this very cool study from @casanova_lab hot off the press at @ScienceMagazine.It shows that very severe #COVID19 is associated with auto-antibodies against type I interferons.https://science.sciencemag.org/content/early/2020/09/23