#Interferon

Ya-Chi Ho

HoLabHIV

SARS-CoV-2: A Storm is Raging: Our Preview/Perspective for Chen on JCI: by day 8 after infection, it's cytokine storm and CD4/CD8 decrease that causes respiratory failure, not viral load. Agree

Rahul Ganatra

rbganatra

1/Should we use #Lopinavir-ritonavir (LPV/r) + #Ribavirin (RBV) +/- #Interferon beta-1b (IFN) to treat #SARSCoV2 #COVID19? Let’s take a look at the data.Here’s: #HowIReadThisPaper on @TheLancet trial of triple therapy

@MacJordan

MacJordaN

The Coronavirus COVID-19 Pandemic: The Real Danger is “Agenda ID2020”, NFC Chip and Vaccinations. #COVID19 #CoronaVirus A thread: It seems, the more there is written about the causes of the

Carl Zimmer

carlzimmer

Big morning for updates to the @nytimes coronavirus vaccine tracker. In fact, I need a thread! https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html 1/9 #covid19 First up: Oxford scientists publish their first cl

Wilson Lab CVR

WilsonLabCVR

New work from our @CVRinfo lab led by @virologist_atu revealing another innate immune 'defect' in horseshoe bats and linking this to why some people get more severe COVID-19:https://www.medrxiv.org/content/10.1101/2021.05.05.2125668

Hironori Funabiki

HironoriFunabi1

Delighted to share our review article, "Regulation and Consequences of cGAS Activation by Self-DNA", by Christian Zierhut @ChriZieri. Free article available until Sep 4.https://authors.elsevier.com/c/1bPjB3QxxSgq3fHere is a thread

David Sinclair, PhD

davidasinclair

Since my Harvard lab closed yesterday, I've been reading and interpreting this week's published papers on #COVID19. What follows is a thread of information, my interpretation, links to sources &

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kafkaintherun

Here is a comprehensive study on the Vaccine(s) that are being tested/studied for COVID-19.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094941/ As SARS-CoV-2 enters human body through ACE-2 (Angotensin coverting enzyme 2) receptors, Angiotensin Bloc

Francisco Marty, MD

FranciscoMarty_

Time to share some thoughts and questions following the .@medrxivpreprint first release of results from the #SolidarityTrial that compared local standard care to #remdesivir, #HydroxyChloroquine #lopinavir_ritonavir and #interferon for trea

A.M.

bhalomanush

Immunology is one of the hardest and most complicated processes to understand. 27 people have won Nobel Prizes for explaining parts of it. I'm going to hazard explaining how pandemic

Alexandre Bolze

alexbolze

1/ Thread on the first 2 papers from the COVIDhge consortium (with my small contribution). The 2 studies show that genetic variants & auto-immunity to type 1 interferons explain 10-15%

Vincent Rajkumar

VincentRK

There are at least 4 possible reasons why some people with COVID have little or no symptoms.1) A rapid immune response that conquers the virus2) Pre-existing cross reactive immunity3) Genetic

Ryan Radecki, MD MS

emlitofnote

I've seen a lot of irritation and frustration for @NEJM and their publication of an uncontrolled case series of #covid19 patients treated with #remdesivir – saying, "great, where's the RCT"?Well,

Vinay Choksi

VChoksi

After struggling with some @CPSolvers cases and having a case of ESR/CRP negative GCA @IMResidencyDuke, I wanted to dive deeper into ESR and CRP to interpret them better. Thanks to

Eric Topol

EricTopol

Nature can be beautiful but also evil.It has brought us the worst pandemic in more than 100 years.What is it about #SARSCoV2 that makes it so nefarious? 1/ As compared

Roland Baker

RolandBakerIII

Confronting the COVID-19 Pandemic with Systems Biology Posted April 10, 2020. [Everything we "know" about SARS-CoV-2 now in question!]https://www.biorxiv.org/content/10.1101/2020.04.06.028712v1 The commonly accepted view that SARS-CoV-2 ent