#Methylation

Happy to share our latest study on site-specific turnover of DNA methylation: https://www.nature.com/articles/s41467-020-16354-x Genomic maps of DNA methylation, while informative about genome activity and cell state, provide only a freeze

there are all kinds of interesting puzzles buried in the grail blood test cancer diagnostic paper A reasonable solution to most of them:There is a lot more signal in DNA

Jacob Schreiber

The more papers I read for a review article I'm writing about ML pitfalls in genomics, the more my faith is shaken in the results from papers that apply machine

Can the stress in your environment affect the genes that your body is expressing? It has been found that in cases of traumatic or chronic stress, this is a possibility.

Magnesium Papi/BowTied Mg🐍🪷

For fertility, Folate metabolism is crucial and is delivered by lots of properly prepared green leaves, liver, and kefir. Folic acid in supplement form should be avoided at all costs,

Investing Panda

investing_panda

Cool innovation in cancer screening: liquid biopsySignals (methylation status) from blood samples + DNA sequencinghttps://www.wsj.com/articles/cancer-screening-leaps-forward-11593973586$ILMN $GH #Grail ARK on DNA methylation: similar to bol

Hanna Faghfoury

Genetic testing: there are so many tests to choose from! Karyotype, Microarray, Whole exome sequencing, they all sound the same. What's the difference? Read on and hopefully things will become

short thread on nominative determinism: last year, @greenygreen1112 and seungjae discovered a novel splice isoform of the neural RBP Fne, which is in the ELAV family. but very few people

Learn Nutrition

learnnutrition_

Ketogenic diet: 14 mechanisms of action #Keto1. Lowers blood sugar & insulin levels2. Decreases leptin3. Produces ketone bodies, an alternate source of energy, instead of glucose4. Changes neurotransmitters, GABA, glutamate,

Super proud to share this work led by the talented @Kira_P_M, PhD student at @LieberInstitute and @HopkinsMedicine ! in this paper we performed whole genome bisulfite sequencing (WGBS) in hundreds

David Sinclair, PhD

Finally had time to carefully read the new preprint that claims to reverse the age of rats by 54%. I spoke to the first author & in this thread ask

I'm very pleased to announce our publication "Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk paediatric cancer" online today in @NatureMedicine https://rdcu.be/b76h9

IE: that "patients faking" video. Here's a story about the time I went to the ER because my HR had been around 150 for hours. Upon admission, I was shaking.

A more polished thread on #epigenomic #biomarkers for #LiquidBiopsy and #CancerScreening: Epigenomic biomarkers are becoming more established for #LiquidBiopsy and #CancerScreening, and we have seen the big players positioning themselves

I'm starting a "Paper a Day" series, where I *plan* to summarize the key results in a handwritten scheme. I tell my students that organic chemistry is best retained through

Sandra Laurentino

1/7Our work on germ cell #ageing in healthy men is out on @AgingCell. A collaborative effort of clinical and basic researchers, 5 institutes, technicians, and many volunteers. #CRU326 @UK_Muenster @WWU_Muenster