#Biomarkers

Eric Fauman

Eric_Fauman

Another paper illustrating the limitations of the TWAS method which I think should lead to greater caution in using TWAS results to assign causality in genetic studieshttps://www.biorxiv.org/content/10.1101/2020.08.31.273458v2@MarylynRitchi

Verity Allan #Rejoin the EU 🇪🇺 #BlackLivesMatter

verityallan

Because Science was inconsiderate enough to have an announcement about a major astronomy finding while I'm on leave, let's pretend to do some outreach (aka wittering on Twitter). #phosphine on

Eric Fauman

Eric_Fauman

Something very comforting about the v high reliability and reproducibility of modern GWAS. I believe the first report of an association between SLC2A9 and uric acid and gout is this

Pigment Cell & Melanoma Research

PCMR_Wiley

It's Friday again! Today #InterviewFriday, we talk to @PatriciaPossik, #melanoma researcher at the Brazilian National Cancer Institute and co-senior author of a comprehensive review on #acral melanoma:https://onlinelibrary.wiley.com/doi

Courtney Boen

CourtneyBoen

I spend a lot of time thinking abt how scientists measure "health," & the benefits, limitations, & trade-offs of various measures (mortality, diagnosis, self-reported, etc.). Each tells us something, but

Ahmad Taqi

Ahmad_Taqi

Remdesivir for COVID-19. Single arm study, very difficult to make any conclusions from it, will have to wait on the ongoing RCT..https://www.nejm.org/doi/full/10.1056/NEJMoa2007016 للأسف قد تكون هذه أسوأ ورقة عملية تنشر

Albert Vilella

AlbertVilella

A more polished thread on #epigenomic #biomarkers for #LiquidBiopsy and #CancerScreening: Epigenomic biomarkers are becoming more established for #LiquidBiopsy and #CancerScreening, and we have seen the big players positioning themselves

Virginia Shalkey Hahn, MD

VirginiaSHahnMD

1/ In press in @JACCJournals JACC: Heart Failure today:Endomyocardial Biopsy Characterization of HFpEF and Prevalence of Cardiac Amyloidosis@KSharmaMD @dkassjhu @lryanek @jvaishnavmd @WendyYingMD @vinisubramanya @EE_Brown42@Marc_Halushka @R

Christine Limonte, MD

christinelimont

Currently attending the @ASNKidney webinar, "Going Beyond the Statement: Dismantling Systemic Racism in Nephrology". Excellent discussion so far! Will share some points that stand out to me here... "Race is

Vineet Chopra

vineet_chopra

There’s a lot of doom and gloom out there when it comes to #CoVID19. It’s true / it’s a bad disease. But we discharged three people home this week after

Genomics Data Science - SFI CRT

GenomicsCRT

Galway, our host city for @GenomicsCRT, is a great place for genomics and the student experience. You can now study genomics at all levels in @nuigalway with the BSc in

Nataniel Lester-Coll, MD

DrLesterColl

On now! @abhiAsolanki discussing the management of locally recurrent prostate cancer after EBRT #ASTRO20 #pcsm #radonc Great discussion of patient selection for salvage therapies and potential outcomes. Bottom line, we

Michael Gensheimer

MFGensheimer

Let’s talk about measuring performance of predictive models/biomarkers. Can we compare AUC across studies to rank models? Recent machine learning papers have had eye-popping AUC values (such as DeepMind's paper

Nicky Whiffin

nickywhiffin

16 months since the first was on @biorxivpreprint, and just over a year since the first was accepted, the 7 gnomAD papers are finally out in @nature, @NatureMedicine and @NatureComms:

Prof. Akiko Iwasaki

VirusesImmunity

Very excited to share this work by the heroic team - @carolilucas Pat Wong @sneakyvirus @tiago21bio et al on “Longitudinal analyses reveal immunological misfiring in severe COVID-19”. A thread on

Adriaan

A_van_der_graaf

Today we're sharing an analysis of the genetics behind two important COVID-19 genes: ACE2 and TMPRSS2. A thread on what we have found 1/9https://www.medrxiv.org/content/10.1101/2020.04.22.20074963v1 @LifelinesNL @serenasanna1 ACE2 and TMPRSS2 are