#RCTs

Sanjay G Reddy

sanjaygreddy

Angus Deaton's article, just published in @TheIndiaForum on 'randomization in the tropics': https://www.theindiaforum.in/article/randomization-tropics-revisited @ramreddy As frequently, I disagree with Deaton on certain points, for instan

Jonathan Kimmelman

KimmelmanJ

Cool study, 'Inferences about drug safety in phase 3 trials in oncology: Examples from advanced prostate cancer' in @JNCI_Now from @JoshDragoMD @gonen_mithat et al 1/https://academic.oup.com/jnci/advance-article/doi/10.1093/jnci/dja

Prof Darrel Francis ☺ Mk CardioFellows Great Again

ProfDFrancis

What should you do when you see something that supports your beliefs? (H/T to @LCC_DrMalik ) Do you *think* wearing a facemask reduces transmission of Covid? Here is Iqbal's enquiry.

𝙟𝙤𝙨𝙝 𝙛𝙖𝙧𝙠𝙖𝙨 💊

PulmCrit

here are my current thoughts on cytokine storm diagnosis, higher dose steroid, and tocilizumab. this *isn't* strongly evidence-based, so if you're an EBM stickler please don't read this thread...(1/5)(more in

Nick Mark MD

nickmmark

BIG NEWS: In January, the unpublished VICTAS trial of vitamin C in #sepsis was stopped after enrolling just 501 of a planned 2000Now data on http://clinicaltrials.gov shows why, and it

Robert M Califf

califf001

Wondered about Sweden? From a friend: I think we are doing quite ok in Sweden. Thankfully the initial rapid increase in number of severe Covid19 patients requiring ICU care has

Sek Kathiresan MD

skathire

So, so frustrating to see this. When you don’t have control group, you really CAN’T estimate efficacy. Controlled studies are being done (some already completed). Let’s wait before declaring success.

Kert Viele

KertViele

(1/6) Interesting discussion on REMAPCAP and AI. I first thought ”ick, an unnecessary sidebar to the real innovations”, then “maybe it’s AI in an overly broad sense of AI”….and now

Ajay Kirtane MD SM

ajaykirtane

1/Here’s a rant about meta-analyses in the CV space. I don’t mean to be disparaging (especially because the first meta-analysis I published was probably the most labor intensive project I’ve

Kevin

kevin_bowen

So wait, am I reading this right that this study didn't even *attempt* to create matched, pseudo-random groups via post-facto stats wankery like the VA paper tried (and failed miserably)

Gummi Bear

gummibear737

My deep dive into “The Only #Hydroxychloroquine Study You Need to Read” by @AmeshAAYou can also consider this a deep dive into HCQ RCTsLong thread coming - I’m not numbering

Dan McIsaac

mcisaac_d

Does labour epidural analgesia cause #autism? Probably not (but only an RCT can answer this question). A thread @CASUpdate @APSForg @OttawaHospital @OttAnesthesia @ASALifeline @SOAPHQ @glbryson @Ron_George @antonchau1 @DrLucieFilteau @Dolor

Chris von Csefalvay

chrisvcsefalvay

Whether #hydroxychloroquine works for #COVID19 or not, it should be for scientists to test it, not for Dr Bright to unilaterally determine what is and isn't sound science. This is

Kim Weeden

WeedenKim

Some thoughts on this @BrankoMilan piece from the perspective of a sociologist whose work is economics adjacent. (I study income inequality & its sources, include rents; gender inequality in wages;

Hold2

Hold2LLC

Thread: Masks and NPIs.This thread reviews information published from Oct 2019 - Dec 2020.The point is to see what was known/believed before & after discovery of COV2.We'll start with research

Prof Francois Balloux

BallouxFrancois

Another meta-analysis based on 5 RCTs (5,577 patients) suggesting HCQ was associated with a ~24% [~3%-41%] reduction in a 'compound metric' of #COVID19 infection, hospitalisation and death. No serious adverse