Sek Kathiresan MD, Discover and Read the Best of Twitter Threads by @skathire

Sek Kathiresan MD

skathire

@UniofOxford @AstraZeneca COVID vaccine (modified chimp adenovirus bearing spike protein) effective!Dose regimen 1 (1/2 dose + full dose): 90% Dose regimen 2 (full + full): 62%Avg regimens: 70%Interim analysis 11K,

Wow, highest documented seropositive rate I have seen in world!200 random sample Chelsea, MA32% test positive antibody J. Iafrate @MassGeneralNews pathology Nearly a third of 200 blood samples taken in

Beautiful paper comparing SARS-CoV-2 antibody assays:custom ELISA assay vs 9 lateral flow assaysKey takeaways: 1. ELISA can be highly specific (100% negative call in 50 pre-pandemic samples)2. LF assays seem

So, so frustrating to see this. When you don’t have control group, you really CAN’T estimate efficacy. Controlled studies are being done (some already completed). Let’s wait before declaring success.