#RCTs

Surbhi Kesar

SurbhiKesar

1/8 In a conversation with one of my profs about yet another RCT 'proving' a well-known field-survey-based result using 'rigorous' data analysis, he remarks: "It is a sign of *dumbification*

Natalie E. Dean, PhD

nataliexdean

This article touches upon many of the concepts we have been thinking about over the last few years. How do we evaluate vaccines/therapeutics during public health emergencies? RCTs are tricky

ice9

__ice9

Eastern Virginia Medical School COVID-19 protocol:https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdfThe EVMS guidelines take an expansive, proactive approach to case management.They try to be

Christopher Graber

glavaidguy

OK, #IDTwitter, we need to talk about y’all’s bashing of the @nejm remdesivir paper.We all want RCTs, but the data collection for this paper started in JANUARY. I didn’t know

Michael Baum

MichaelBaum11

Yesterday, following a challenge, I was directed to this study that suggested screening for breast cancer could save lives."All‐cause mortality versus cancer‐specific mortality as outcome in cancer screening trials: A

Deborah Cohen

deb_cohen

Facemasks a thread - on Friday we broadcast a film looking at some of the scientific debate around masks. I want to respond to some of the points made by

Todd Lee

DrToddLee

Some thoughts about the recent publication of the DASH trial for posterity @MatthewPCheng @SamuelDM18 @AlexLawandi @GBL_Unit @McGill_DOM @IDIGHProgram Articlehttps://doi.org/10.1093/cid/ciaa1000With thanks to @ABsteward for letting us know

Kevin Donovan

kevindonovan

A new working paper by World Bank economists is rightly provoking the ire of critics like @EconKilljoy, @gchelwa, @godwinmurunga, and @peripheralecon. The paper reports the results of a randomised controlled

Kenneth Rockwood

Krockdoc

Great question. Most key trials preceded the Clinical Frailty Scale. @GrahamEllis247 will know best, but here’s my read. (A 7-part thread; forgive me.) Back in the late ‘70s (when I

Josh Budlender

joshbudlender

This is outrageous - an RCT cutting off water to tenants in Nairobi "slums" to see if it induces their landlords to pay the utility bill. And reading the paper

John Mashey

JohnMashey

f1/ Trump keeps pushing people to (Hydroxy)Chloroquine. I’ve been collecting & annotating credible information from @UCSF experts on COVID-19, as it appears, in the subthreads ofhttps://twitter.com/JohnMashey/status/1245825681306431491 CV1-This t

Flavio Abdenur

AbdenurFlavio

1/ There are now about 20 randomized clinical trials (RCTs) of ivermectin for covid. They overwhelmingly show reductions in mortality, when used in adequate doses and in patients who are

Jessica Bunin, MD

jessica_bunin

MICU Day #7: Disclaimer: I am an Intensivist, not an ID doc. What follows are lessons learned from 7 days of caring for COVID patients. There are no RCTs or

Jake Dunning

OutbreakJake

This is a great paper about CQ/HCQ and #COVID19, supporting the argument that we should not be dishing it out like Smarties for compassionate use (same goes for lots of

Eric Topol

EricTopol

Adding to the above slide of no evidence, update today:@NIH panel recommends against Hydroxychloroquine (H) and Azithromycin (A)https://www.npr.org/sections/coronavirus-live-updates/2020/04/21/840341224/nih-panel-recommends-against-drug-combination-t

Trisha Greenhalgh 😷 #CovidIsAirborne

trishgreenhalgh

1/n Thread for healthcare providers on video consultations (VCs) as a partial solution to #COVID pandemic. I’ll cover RESEARCH, CLINICAL, TECHNICAL, STRATEGIC and OPERATIONAL issues.Mute this thread if not interested