#RCTs

Andrew Morris

ASPphysician

Inhaled budesonide. A thread.There has been a lot of energy being given to budesonide in COVID-19, with some tweeterati referring to it as having "strong evidence".Also, FPs/ED MDs would love

Pauli Ohukainen, PhD

POhukainen

I find this quite interesting; the estimates for the association between wearing a #mask and some coronavirus infection in non-hc setting (0.56, 95% CI: 0.40-0.79) is roughly the same magnitude

Helen Ward

profhelenward

The acrimonious debate about masks between usually sensible people seems unhelpful. Those in the “no evidence, need an RCT, they do harm” camp seem over-anxious, and those saying they are

Natalie E. Dean, PhD

nataliexdean

Two interesting examples of how randomized controlled trials could build evidence for policy decisions - whether to offer alternative housing for isolation, and re-opening schools. Useful to start thinking now

Tanya Selak

GongGasGirl

John Laffey Professor Anaesthesia and ICM Galway. Update on Covid19 research. The @AAGBI webinar continues. Knowledge is rapidly evolving. There was nothing known about #covid19 until a few months ago.

Joshua Niforatos, MD, MTS

reverendofdoubt

I gave @Surgisphere the benefit of the doubt. I believe this data is very possible to have. Other companies have similarly large EHR datasets, such SVS, Explorys, etc. I have

Nicole Baldwin, MD, FAAP

NicoleB_MD

1/9 Ankyloglossia and Other Ties: What is the Evidence? https://cdmcd.co/Zwj5PE #AAP2020 Ankyloglossia = tongue tieDiagnosis is exponentially increasing:US Birth Rate 2000: 4M; 2012: 3.9MAnkyloglossia dx 2000: 5K; 2012: 33KFrenotomy 2

The Sharing Scientist

ScienceShared

A pretty great thread summarising medical/public health interventions which sounded logical and like the obvious thing to do, but RCTs showed they weren't.Nice @lancet article on screening linked here also.And

Mike Steinman

MikeSteinman

Some thoughts on OPTIMISE trial just published in JAMA - RCT of deprescribing hypertension meds in adults age 80+ with SBP

Anish Koka

anish_koka

Thread on some details of @freopp plan:Assumptions being made: 1. Repeatedly testing the entire population may require 22 million tests/day - Paul Romer2. Antibodies may not equal immunity3. Antibody tests

Robert Plenge

rplenge

The immune system is critical in the fight against SARS-CoV-2 infection. But what happens when the immune system turns against the body itself? Read this blog.thread to learn more, including

Aaron Richterman, MD

AaronRichterman

Really nice to see this WHO analysis in JAMA (along w 3 RCTs) put to bed the importance of corticosteroids in ventilated patients w COVID-19. A lot of good stuff

Foggy Anabasis

foggyanabasis

The problem with these mid-brow "we've always been at war with East Asia" takes is that some people have memory. After the 1920s, when the health establishment noticed that mask

Kashif Pirzada, MD

KashPrime

It's ridiculous that we lack a framework in modern medicine to adapt/innovate to a new disease like #Covid-19. There is a fierce debate raging in medical and scientific circles between

Leora Horwitz

leorahorwitzmd

I have turned down several press requests to talk about Trump's treatment because I am not his doctor and don't know the situation. But the questions people asked made me

Kevin Kuriakose

infectiouskiwi

Since there are no proven therapies for COVID-19 at this time, learning to spot the charlatans coming out of the woodwork will be helpful. Here's a very basic guide on