Natalie E. Dean, PhD, Discover and Read the Best of Twitter Threads by @nataliexdean

Natalie E. Dean, PhD

nataliexdean

A sketch to explain how a new variant may appear milder even with no change in underlying virulence. This can occur because, when calculating the fraction of cases that are

I had the opportunity to write a comment about findings from a large vaccination cohort study in Scotland. I use the comment to discuss some of the challenges of observational

Astrazeneca/Oxford get a poor grade for transparency and rigor when it comes to the vaccine trial results they have reported. This is not like Pfizer or Moderna where we had

We focus a lot on QUANTITATIVE data - test positivity, number of hospitalizations - but there is also enormous value in QUALITATIVE data. If we interviewed a hundred contact tracers

VACCINE EFFICACY 101: A biostatistician's primerTen tweets to cover:- How is vaccine efficacy calculated?- Distinguishing between infection, disease, & severe disease.- Measuring reduced infectiousness.- Vaccine efficacy vs. effecti

A thread for fellow statistical analysis plan nerds (warning: math ahead).From Pfizer's protocol, vaccine efficacy will be estimated by the incidence rate ratio. A tutorial on how this corresponds to

What I don’t want:- A return to stay-at-home ordersWhat I do want:- Major investment in proactive solutions that allow us to return as close to normal as possible What do

Overdispersion in action. In this church cluster, a single index case resulted in 53 (!) secondary blue cases. Yet, each blue case resulted in only a few tertiary cases. In

This article touches upon many of the concepts we have been thinking about over the last few years. How do we evaluate vaccines/therapeutics during public health emergencies? RCTs are tricky

Really appreciate this from @StevenSalzberg1. There are important debates about how we do (or do not do) things differently during emergencies, and I think it is good for the public

Respectfully, I really disagree with this view. We should only start vaccinating widely when we are confident a vaccine is safe and effective. Why? A few reasons...https://twitter.com/stevensalzberg1/status/1289890177683316739 Widespread us

Pleased to share my contribution to @BostonReview's "Thinking in a Pandemic" series. My focus was applying solution-based thinking to move us towards our goal of living safely. I would love