#Camostat

Lu Chen

houndcl

https://clinicaltrials.gov/ct2/results?cond=&term=Camostat&cntry=&state=&city=&dist= 5 Camostat trials proposed based on ∅.If TMPRSS2 not expressed, water-like activity at 50uM. Otherwise, some inhibition at 10uM https://www.biorx

Matt Hall

cispt2

OK so let's talk about camostat, because I'm starting to worry about it as a #COVID19 repurposing candidate. It emerged based on this Cell paper, but a LOT of assumptions

Anand Ranganathan

ARanganathan72

Demographic breakdown by Age for India and Italy, and Death Rate by Age for #COVID19. #CoVID19Global Case Fatality Rate (CFR): 3.5%[(3800 deaths / 110,000 confirmed cases) X 100]1. CFR will

Treponema Pallidum

sulley_ibraheem

Denmark will start a clinical trial of a drug named camostat mesylate tomorrow—barely 1 month after a Cell paper showed the compound can prevent the novel coronavirus, SARS-CoV-2, from entering

Sripal_s

sripal_chandra

The COVID targets- RNA virus. SARS COV2 shares nearly 80% genetic analogy with previous SARS COV particularly for spike glycoprotein. There are two subunits of spike glycoprotein but this is

Tyler Black, MD

tylerblack32

So I'm going to use a dude as an example. Sorry, @prodreamer1, but you are an example an onslaught of poor armchair science.Currently, this "retired MD" is going at me

ice9

__ice9

COVID-19 antiviral EC50s expected hittable:- amodiaquine- atazanavir- camostat- chloroquine- ciclesonide- dipyridamole- doxycycline- favipiravir- hydroxychloroquine- HTCC polymer- IFN-α 2b- indomethacin- itraconazole- mefloquine- nelfinavir- niclosam

Jason Pogue

jpogue1

I promise that if #hydroxychloroquine was an effective therapy for #covid19 we would tell you. Many of us (myself definitely included) were hopeful that it would be at the onset

Rafael Fonseca MD

Rfonsi1

*** COVID19 and males***Is infection with SARS-CoV-2 more virulent among males, and if so why? Can we do anything about it, or use this information for treatment purposes. This thread

Aaron Richterman, MD

AaronRichterman

Here is @EricMeyerowitz and my #COVID-19 literature UPDATE 3/25-4/8Slides: https://docs.google.com/presentation/d/13nbSCnJDQKtidyZR663GkmE5cX9wCwa7U5hwHWDgRnY/edit?usp=sharingRecording:https://www.youtube.com/watch?v=LgkMKLpsCusKey messages with stud