#Microthrombi

I think the most overlooked factors right now are probably:1) risk of pulmonary microthrombi (practice appears to be converging on prophylactic enoxaparin, see e.g. Yale guidance)2) secretions, risk of hyaline

Miguel Rodríguez Rubio

miguelrdgzrubio

I’m reading lots of people talking about encephalopathy after sedation weaning in #COVID19 patients. Lots of theories including microthrombi, inflammation and hypoxic-ischemic lesions. Probably all of those play a role,

Severe #COVID19 induces an endotheliitis: a pseudo-vasculitis phenotype with a viral renal-lung syndrome and ARDS. Nephrologists report AKI without shock/renal hypoperfusion. Microvascular endotheliitis also explains cardiac manifestations & thro

Kashif Pirzada, MD

Front-line providers need to consider anti-coagulating their rapidly deteriorating COVID-19 patients. Could it be that severe endothelial dysfunction, resulting in microvascular thrombosis, is playing a major role in the rapid

Ed Ostrin, MD, PhD

There's an emerging theory that the profound hypoxia by COVID is due to a sort of hemoglobinopathy caused by direct viral protein binding to heme. I suppose anything is possible,

Daniela Hermelin, MD

MaternalFetalMedicine #Blooducation conference. Topic: #TTP in pregnancy. We focused on thrombotic microangiopathic hemolytic anemias & shear wonder of the #schistocyte. Rock, Paper, Scissors, Shoot. Let's recap on the some of

Vinay Prasad MD MPH

Ok, here is a little #Tweetorial about #COVID19 and whether, outside of a controlled trial, we should be using different:1. rules for anti-coagulation/ lytics2. ventilatory settings in ARDS3. anti-virals/ anti-inflammatories

Erin C. Sanders, MSN, WHNP-BC (She/Her)

1/ Big thanks all of you on @Twitter for the interest in my thread regarding current literature on #microthrombi and #COVID19! It’s late, so of course, more thinking and more

Stage II of Virus and Bacteria Synergistic Infection of Covid-19: A physical model 0. Recap:Virus breaks cell and ECM adhesion, letting the endogenous bacteria in:https://twitter.com/joshux321/status/1264387117200756736?s=20The virus is lar

Hannah | Hehua Huang

1/6 Two proposed interventions from Li Taisheng, the director of ID dept. of Peking Union Medical College Hospital; he works on the frontline for #SARSCoV2 and SARSCov11. "Give IV immunoglobulin

Dr Tarun Deep Singh

Lets try and learn some basics of the COVID-19 illnessSo to understand what’s happening you need to understand the story behind it.(A Thread) 80% people will have flu like sicknessMild/Initial

Adeel Shahid, MD

Trying to understand all the manifestations of #COVID19 and #ACE2 receptor seems to be the key, Feel free to add info I miss. #SARS_COV_2 enters cells expressing this, abundant in

from the Head of ICU at the Royal Free. Please feel free to disseminate further. “Dear All, I have just finished a very useful ICU / NHS Nightingale teleconference, the

Shematologist, MD

So I was hoping to avoid a COVID heme #tweetorial but with >50% of the votes on my survey, the people have spoken. (but hold on, this is going to

Erin C. Sanders, MSN, WHNP-BC (She/Her)

THREAD 1/ I hope no one believes that I am an expert on #SARSCoV2 or believes that “I” think I am an expert on #COVID19 In an effort to contribute

Aaron Richterman, MD

AaronRichterman

Here is @EricMeyerowitz and my #COVID-19 literature UPDATE 3/25-4/8Slides: https://docs.google.com/presentation/d/13nbSCnJDQKtidyZR663GkmE5cX9wCwa7U5hwHWDgRnY/edit?usp=sharingRecording:https://www.youtube.com/watch?v=LgkMKLpsCusKey messages with stud