#Immunogenicity

Dr. Nahid Bhadelia

I see a lot of question re flu shot timing in my timeline. Since I'm on clinical service, doing one single main tweet on it here: Generally CDC recommend Sept-Oct

No time like now for my first thread! Thought I would give my take on the COVID-19 vaccines that have published results for human trials. And as everyone loves a

NEW—Preliminary results from Russian trials find that #COVID19 vaccine candidates led to no serious adverse events and elicit antibody response https://hubs.li/H0vGWRW0 Thread (1/8) The new paper reports the findings of two

Florian Krammer

florian_krammer

1) So, this is the first 'serious' preclinical data I have seen for an actual vaccine candidate. This one is an inactivated SARS-CoV-2 vaccine made by Sinovac. Seems to work

1) Russia’s approval of an early vaccine candidate is reckless as it places domestic- and geo-politics ahead of science and medicine. According to the @WHO vaccine tracker, the Gamaleya candidate

Are we testing #COVID19 vaccines for kids?I often see an assumption that the COVID vaccines being trialed will be available for kids at the same time as adults assuming efficacy.

FYI on the #COVID19 #RussianVaccine - tested in an open label, non-randomized phase 1+2 (no placebo) in 38 people combined. Safety monitoring for 2 mo only. cannot even detect common

We have a lot riding on the Moderna COVID vaccine, but little insight into how it’s performing in trials. Tiny peek under the hood from their investor press release here:

Joyce Sanchez, MD

Wondering whether to get the flu vaccine now or wait until later in the season? I found conversations with @EpiEllie and @BhadeliaMD helpful. A thread 1/ Traditionally, flu peaks

Thoughts from my piece in BMJ today about SPUTNIK #vaccine : Need the best, safest, most durably protective vaccines. Can’t identify these unless we have a transparent, peer-reviewed comparative evaluation

SARS-CoV-19 Preprints

1/11 Analysis of humoral immune response in #COVID19 patients provides key insights for #ConvalescentPlasma therapy and #Vaccine research: https://www.medrxiv.org/content/10.1101/2020.03.30.20047365v1 2/11 A pseudotyped-lentiviral-vector-based neutra

Michael Lin, PhD-MD

Here's something that's at once good news and extremely disheartening. Valneva, the only Western pharmaceutical to produce an inactivated virus vaccine for COVID19, today announced they are *starting* their phase

Both #China & #Russia approved #COVID19 #coronavirus #vaccines for use outside of clinical trials before #phaseIII was completed. This is quite an unusual move; many think the #US will follow

Ashish K. Jha, MD, MPH

Almost every day, I am asked about the Russian vaccine.Lots of questions of whether we should "take it" or not.My answer has been -- no idea -- haven't seen the

Chris van Tulleken 🏳️‍🌈

Since the extraordinary initial announcement last August, everything about Sputnik V has seemed worthy of detailed scrutiny...My piece in @bmj_latest on Open Data, the weaknesses of peer review and #Sputnikvaccine

Nunca vi 1 cientista

A Rússia publicou os resultados iniciais da sua polêmica vacina, aprovada antes mesmo de terminarem os testes clínicos.Vou levantar aqui no fio os pontos positivos e negativos do estudo https://www.thelancet.com/journals/lancet/article/P