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Almost every day, I am asked about the Russian vaccine.
Lots of questions of whether we should "take it" or not.
My answer has been -- no idea -- haven't seen the data.
Now we have data!
So let's look at the data -- what does it tell us?
Thread
Lots of questions of whether we should "take it" or not.
My answer has been -- no idea -- haven't seen the data.
Now we have data!
So let's look at the data -- what does it tell us?
Thread
New study out in today's @TheLancet with real data.
So that's exciting
Key findings:
First, these are adenovirus vector vaccines. Like the Oxford Astrazeneca, CanSino and others
Nothing new or particularly innovative here
Link to study: https://www.sciencedirect.com/science/article/pii/S0140673620318663
So that's exciting
Key findings:
First, these are adenovirus vector vaccines. Like the Oxford Astrazeneca, CanSino and others
Nothing new or particularly innovative here
Link to study: https://www.sciencedirect.com/science/article/pii/S0140673620318663
And?
Two vectors, 76 patients
Relatively young, healthy patients in 2 hospitals
And bottom line is largely positive:
Recipients generated humoral (antibodies) and cellular (T cells) immune response
Lots of side-effects (fevers, pain) but nothing serious.
Short-term
3/5
Two vectors, 76 patients
Relatively young, healthy patients in 2 hospitals
And bottom line is largely positive:
Recipients generated humoral (antibodies) and cellular (T cells) immune response
Lots of side-effects (fevers, pain) but nothing serious.
Short-term
3/5
Worth noting, as editorialist does, that immune response was robust.
And it was in healthy people.
So, Russcian vaccine joins others including the one from CanSino, Moderna, Astarzeneca, etc in showing immune response.
So what does this mean?
4/5 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31867-5/fulltext
And it was in healthy people.
So, Russcian vaccine joins others including the one from CanSino, Moderna, Astarzeneca, etc in showing immune response.
So what does this mean?
4/5 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31867-5/fulltext
Bottom line:
We do NOT know if Russian vaccine is safe (small, short-term study only) or effective (does it prevent infection or severe infections)?
Russians "approved" vaccine without knowing if it worked/was safe
This study is good -- but doesn't answer those questions
5/6
We do NOT know if Russian vaccine is safe (small, short-term study only) or effective (does it prevent infection or severe infections)?
Russians "approved" vaccine without knowing if it worked/was safe
This study is good -- but doesn't answer those questions
5/6
Russia approving vaccine without Phase 3 trial irresponsible
We should ensure we don't follow same path
Am hopeful Russian vaccine will eventually be deemed safe/effective
World needs all the vaccines we can get
Science moving fast. Let's do it right -- wait for the data
Fin
We should ensure we don't follow same path
Am hopeful Russian vaccine will eventually be deemed safe/effective
World needs all the vaccines we can get
Science moving fast. Let's do it right -- wait for the data
Fin
