#Lopinavir

Latest paper from RECOVERY trial:In patients admitted to hospital with COVID-19, lopinavir–ritonavir did not reduce 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or

More results from the RECOVERY trial - Hydroxychloroquine:Among patients hospitalised with COVID-19, hydroxychloroquine (HCQ) did not improve 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical

The power of large, pragmatic randomized trials. Conducted by academic researchers using an adaptive trial design (#MAMS), and you’ve got a winner. Strong reasons why publicly funded research is so

COVID-19 antiviral EC50s expected hittable:- amodiaquine- atazanavir- camostat- chloroquine- ciclesonide- dipyridamole- doxycycline- favipiravir- hydroxychloroquine- HTCC polymer- IFN-α 2b- indomethacin- itraconazole- mefloquine- nelfinavir- niclosam

Following a rigorous review and data synthesis, the panel agreed on seven treatment recommendations. They note that in their recommendations, the word "recommend" indicates strong recommendations, and the word "suggest"

The preprints of the #SOLIDARITY trial are out on MedRxiv. While many may lament that all four drugs tested did not show benefit, this is a remarkable trial for many

New study by @IdoAmitLab on scRNA-seq in mild (n=3) vs severe (n=6) COVID-19 patient, w/ computational disentangling of cells directly infected by SARS-CoV-2 vs those indirectly impacted. https://www.sciencedirect.com/science/article/pii/S00928674203

There has been a lot of talk of Hydroxychloroquine for the treatment of Covid 19. And like Trump says"Try it,what's there to lose ?"Let me tell you that it is

Once again people message me to counsel their fears.They read/saw something by the VILE, DUPLICITOUS & CORRUPT MSM that @realDonaldTrump has repeatedly said are the ENMITIES of the American People.FUCK.

David Boulware, MD MPH

What are the limitations of observational registry studies? One major issue is confounding by indication. How physicians act is not the same as a Randomized Clinical Trial testing a therapy

My thoughts on #SOLIDARITY results thus farStrengths:Huge size, high power n=11,266Objective endpointHighly generalisable (405 hospitals, 30 countries, all 6 WHO regions). Groups well matched. High compliance with protocol. Not sponsored

Michel Zeitouni, MD

#Thread 1/ Les soignants que nous sommes sont les 1er à vouloir trouver un traitement contre #COVID19. Mais il est difficile de tirer une conclusion sur l'efficacité de #Hydroxychloroquine #azithromycine

Saurabh Naithani(Pahadi)

Why #LAURUS is risingLaurus has three segments1.Generic Api2.Generic FDF3.Custom synthesis and ingredientsGeneric Api almost 55% of businessFirst line products-Lamivudine, DolutegravirSecond line products-Lopinavir Ritonavir DarunavirDolute

https://naspa.us/resource/hydroxychloroquine-chloroquine-and-azithromycin/U.S. state rules on prescriptions for [hydroxy]chloroquine vary quite widely, according to local political posturing, affinity for red tape, etc.Be sure to remember your prefer

Esther Choo MD MPH

Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection(summary in the thread below)https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/?fbclid=IwAR0Mi

This is my definitive statement about my medications/treatments for #coronavirus/#COVID19/#COVID_19. Please note: it corrects errors in past statements of mine, for which I apologize.#LatsCovid19Journal Caveat: I'm not a doctor or