Cellular #enzymes, like those responsible for building glycans, are sloppy & make mistakes frequently!

Despite this, only a small range of glycan chains are found to be associated with a specific #protein!

How is the #variability of glycan chains so tightly-controlled in cells?
The study shows that multi-compartment synthesis can greatly increase the range of glycan chains a cell can specifically produce!

Read more about their journey in this piece by @SiddhrthKnkaria, with illustrations by @dhanya_bharath!

#SciComm #SciArt

https://theory.ncbs.res.in/news/building-biomolecules-one-step-time">https://theory.ncbs.res.in/news/buil...
Read more about their study,

"Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes"

in this thread by Dr. Mukund Thattai: https://twitter.com/thattai/status/1277588401152114689">https://twitter.com/thattai/s...
You can follow @NCBStheory.
Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled: