💊NICOTINE - The Writer's Nootropic (THREAD)


This curious and misrepresented compound has a myriad of interesting benefits, including increases in wakefulness, motivation, alertness and creativity, as well as multiple neuroprotective benefits.
🧠Nicotine has been shown to increase activity across both hemispheres of the brain. It increases your alpha brain wave state so you get better attention + better creativity.

If you’re an athlete, you’re better able to enter into the zone
!
Nicotine mimics the neurotransmitter acetylcholine + directly activates acetylcholine receptors.

This leads to increases of catecholamines such as adrenaline + dopamine; this mechanism underlies both potential addiction and FAT BURNING!
For the most part Nicotine increases adrenaline + works through beta-adrenergic receptors (the molecular target of ephedrine); this increase in adrenaline mediates the increase in metabolic rate. There is also an increase in lipolysis (how available fatty acids are to be burnt)
The increase in catecholamines also underlies many benefits of nicotine on cognition (attention and focus mainly) while the acetylcholine mimicking promotes a nootropic effect inherently
♂️ Nicotine also acts as an anti-estrogenic compound, inhibiting aromatase and one of the two estrogen receptors directly

This is important for a man that wants to have more free testosterone availability and lessen aromatization of testosterone and estrogens
Nicotine works with the acetylcholine mechanism to exert anti-inflammatory effects, also reduces TNF alpha production and cytokine production. It can assist with patients who have inflammation due to ulcerative colitis.
Nicotine has been studied and PROVEN to improve your fine motor skills and also your short-term memory, your long-term memory and what’s called your working memory.
🌆EVENING BUZZ: Nicotine is useful for an increase in alertness later on in the day that won't affect your sleep like caffeine does. There is some evidence to suggest Nicotine actually increases the quality of deep sleep.
In those who like microdosing LSD, you can actually get some of the same type of what are called bilateral neocortical activations via the use of nicotine
☕️ COMBO WITH COFFEE

Many writers swear by the combination of coffee and nicotine - It's my personal favourite *getting shit done* hack.

I have 3 shots of espresso (on ice) with a 4mg Nicobate lozenge and go wild
⁉️HOW TO USE:

I recommend starting with 2MG, the dose can be quite uplifting to start - be wary and if you feel headspins or nausea then remove the lozenge/Zyn from your mouth and wait until you chill out a bit. Getting #nicsick is not fun.
On the downside!

Nicotine IS addictive and when you try to quit nicotine you get strong cravings, increased appetite, sleep disturbances + a little bit of irritability and restlessness. Similar to caffeine.
Potential side-effects of nicotine are similar to acute side-effects of other stimulants such as ephedrine, yohimbine, or caffeine due to increasing catecholamines
This can be avoided by smartly limiting your amount and taking days off nicotine similar to how I recommend you utilise caffeine.

For me, I won't have more than 10MG a day of nicotine (2 4mg lozenges usually).

I recommend having days where you don't consume any at all
You don't have to smoke!

Nicotine can be consumed without smoke purely in lozenges, chewing gum, chewable toothpicks and sprays. I personally use a brand called Zyn (please sponsor me) or Nicabate Lozenges
Anecdotally, when I use nicotine I feel:

- more 'charged'
- more masculine energy
- focused
- GRRRRR
- IN the gym, you BOMB the weights
- Less anxiety
this thread was brought to you by espresso and nicotine
You can follow @SolBrah.
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