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Of the 9 hallmarks of aging, half or more can be modulated by one factor: better insulin sensitivity.
Having good insulin sensitivity, and low fasting insulin, is arguably the best way to a long life free of chronic disease. https://www.sciencedirect.com/science/article/pii/S0092867413006454
Having good insulin sensitivity, and low fasting insulin, is arguably the best way to a long life free of chronic disease. https://www.sciencedirect.com/science/article/pii/S0092867413006454
How to get good insulin sensitivity?
1. Good body composition, i.e. a relatively high amount of muscle, and a low amount of fat mass, especially visceral fat.
Anything that promotes good body composition therefore fights aging.
1. Good body composition, i.e. a relatively high amount of muscle, and a low amount of fat mass, especially visceral fat.
Anything that promotes good body composition therefore fights aging.
2. A diet of whole, minimally processed foods, especially one free of seed oils, sugar, and refined grains.
Ketogenic diet (very low carbs) has additional longevity benefit. https://www.sciencedirect.com/science/article/pii/S1550413117304904
Ketogenic diet (very low carbs) has additional longevity benefit. https://www.sciencedirect.com/science/article/pii/S1550413117304904
3. Exercise. High-intensity exercise especially depletes glycogen and leads to better insulin sensitivity because of that.
Resistance training leads to better body composition. (See item no. 1) https://link.springer.com/article/10.1007/s00421-004-1307-y
Resistance training leads to better body composition. (See item no. 1) https://link.springer.com/article/10.1007/s00421-004-1307-y
4. Intermittent fasting. Leads to increased autophagy (as does exercise), and that's a requirement for life extension.
https://www.jci.org/articles/view/73946
https://www.jci.org/articles/view/73946
There are many other things you can do, but these are the Pareto 80 of longevity in our world of overnutrition, underactivity, and high body fat.
