Joanna Poole 💙, Discover and Read the Best of Twitter Threads by @Jopo_dr

Joanna Poole 💙

Jopo_dr

reading more into dynamics of 'sepsis' - which do vary a little by source and organism, but generally a period of intense aggression is followed by immune paresis - predisposing

What is an mRNA vaccine? One that instructs the human host cell to make isolated viral proteins (not the whole virus just a surface protein!) so the immune system learns

Stuck at home with a temp and myalgia. 10 minute teaching session today is PHYSIOLOGY. The best reflex no one has heard of, and causes 'tourniquet pain', AKI and post

Every so often I see people reassured when actively bleeding patients have a systolic BP of 100. To get a ballpark multiply their MAP by 80 and then divide that

Cells and Organelles as ancient Gods. (Niche, I apologise.) Red Blood Cells. Hermes. The winged heel messenger god. God of heralds (low sats), travellers (oxygen) and thieves (malaria). Medics are

Albumin is the most prevalent protein in human blood. It's also huge, and shouldn't leak from healthy endothelium. But it is also a sponge in the sense it can bind

So. Now I am recovering from profound terror from the DMs. (And having had actual phone calls with some lovely twitter people). I realise. That on mastodon. Not enough people

Role of BCG vaccine in protection. If like me you have been v confused why TB and covid have anything in common...read on.... First of all people noticed that people

CRP - what I wish I’d been taught! This (large!) protein comes as a pentamer of units 23 k-daltons. It has equivalents in almost all species and is found on

Hospitals in ancient Egyptian scenes. People requesting anaesthetic cannulas. Radiologists weighing your heart and truthfulness before accepting a CT request Attempting to dress new people in full PPE Going out

Royals as anaesthetists. if unwatered by 11am when patients have unexpectedly got a working cannula, and printed labels when the bleep to resus comes consultant and trainee when gave saline

D-Dimer: D-dimers are a degradation product of fibrinogen, a mesh of fibrils that stabilises platelet plugs. They represent two D-domains of fibrinogen joined together, and a cleavage point in fibrinogen