#Equipoise

Tiens, dans cet article Lagier et Raoult citent le fameux article « parachutes » du BMJ.Source : Lagier JC, Raoult D. Deadly infectious diseases such as Ebola: the parachute paradigm. Clin Microbiol

Alex John London

1. My new paper with @kimmelmanJ is out at @ScienceMagazine. “Pandemic Research Exceptionalism” is the idea that the urgency of a crisis warrants lowering #research standards. We argue against this

Christina Henson, MD

My head and neck people: are you doing 3D or IMRT for early stage larynx these days? If IMRT, how often are you getting CBCT? I know what I “grew

I listened to @TheUSMLE podcast about Step 2 CS in the hopes of learning about how the virtual CS exam is being validated (as a reliable predictor of clinical skills,

Facemasks a thread - on Friday we broadcast a film looking at some of the scientific debate around masks. I want to respond to some of the points made by

This is a great paper about CQ/HCQ and #COVID19, supporting the argument that we should not be dishing it out like Smarties for compassionate use (same goes for lots of

(1/12) I receive emails warning about hackers targeting COVID data. Huge issues..it’s a crime and a danger to trial integrity. But also begs another discussion…if your loved one could be

Natalie E. Dean, PhD

Two interesting examples of how randomized controlled trials could build evidence for policy decisions - whether to offer alternative housing for isolation, and re-opening schools. Useful to start thinking now

Prof. Raoult in Marseille, an international star of the COVID pandemic, has very strong opinions on evidence based medicine.I share bits, in my own (unauthorized) translation for educational purposes. Full

Apothicaire Amoureux

Avec une définition incorrecte d’un groupe placebo. La groupe placebo n’est bien entendu un groupe SANS MÉDICAMENTS mais un groupe qui va recevoir le traitement utilisé dans la pratique clinique

Just want to expand on this quickly then it’s back to writing papers https://twitter.com/lachelle_dawn/status/1283771370476834822 So the study referenced in this @statnews piece is a systematic review of FDA’s “Exception from

DEBATE: Should government #policy interventions evaluated in #stepped #wedge #trials be considered ‘research interventions’ and reviewed by the research ethics committee? An exchange in @ClinTrialsJ. #researchethics #steppedwedge #REC 2

Holly Fernandez Lynch

Finally had a chance to review FDA's COVID vaccine development guidance: https://www.fda.gov/media/139638/download. Hard to improve on @AlecGaffney's excellent thread, but here are a few more thoughts.https://twitter.com/HollyLynche

AndrewMoorepain

Thread about clinical evidence on efficacy in the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia (http://bit.ly/3qZ94FV ). Fifteen slides starting with the Task Force composition and contents. Delighted to

1/ Thread on evaluating benefits vs harms of masks for infectious diseases & #covid19. orWhy i think the claim that masks have equal probability of causing harm & benefit is

Now the thrombocytopaenia/ thrombus evidence with ChAdOx is clearer- some thoughts on what this means for populations and individuals There are 3 questions 1) what should we do at