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@FatEmperor - ever heard of glycosylated ferritin ? I think it's something you should look into. (In normal individuals, 50-81% circulating ferritin is glycosylated;
glycosylated ferritin has a longer half-life (~50 h) than non-glcosylated
ferritin (5 h).)
glycosylated ferritin has a longer half-life (~50 h) than non-glcosylated
ferritin (5 h).)
Here's where I got the data from. http://www.acb.org.uk/docs/default-source/committees/scientific/amalc/ferritin.pdf - I was researching how to distinguish between elevated ferritin from iron excess vs. (inflammation and other sources). And I know you are a "root cause" type of guy.
since glycosylated ferritin lasts longer than ferritin, elevated ferritin (which includes both) is an indirect measure of hyperinsulinemia / hyperglycemia. I see sooooooo many people in the mid 300s (normal 22=-275 ug/L).
Another lab's normal is 15 - 517 ug/L. I think they just changed the range. Why deal with chronic hyperinsulinemia / hyperglycemia when you change just change the range and "it's normal". I've never seen an upper level of normal in the 500s, until today. Weird.
Children have typically have lower ferritin than adults. Why would that be ? In males, the median ferritin level increased from 23 mcg/L at ages 12-16 years to reach a plateau in the 120s after age 32. Women stayed in the 30s til menopause, after which rose to 80 mcg/L. Hmmm.
