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DID THE MONKEYPOX (MPXV22) OUTBREAK COME FROM A LAB?
location, transmissibility, number and type of mutations strongly suggest so
disclaimer: this is a PRELIMINARY analysis, a first look, an invitation to an open discussion,
rt!
I hope to be wrong.
But the data...
a
1/x
location, transmissibility, number and type of mutations strongly suggest so
disclaimer: this is a PRELIMINARY analysis, a first look, an invitation to an open discussion,
rt!I hope to be wrong.
But the data...
a
1/x
Disclaimer 2:
Please leave all your
-ad hominem/you're not a virologist
-monkeypox is harmless
-but some expert said something else
-you're a conspiracy theorist
-first prove it 100%
arguments at home.
Point out
-analytical mistakes
-opposing data
-better explanations
please!
2/x
Please leave all your
-ad hominem/you're not a virologist
-monkeypox is harmless
-but some expert said something else
-you're a conspiracy theorist
-first prove it 100%
arguments at home.
Point out
-analytical mistakes
-opposing data
-better explanations
please!
2/x
Let's get to the facts:
1) LOCATION
The case numbers suggest that the MPXV22 outbreak started in Europe, likely in the London area: There was one patient who travelled from Nigeria, but he was isolated and his contacts traced.
All others outbreaks started in Africa.
3/x
1) LOCATION
The case numbers suggest that the MPXV22 outbreak started in Europe, likely in the London area: There was one patient who travelled from Nigeria, but he was isolated and his contacts traced.
All others outbreaks started in Africa.
3/x
2) TRANSMISSIBILITY
MPXV22 rapid spread is highly unusual.
Increased transmissibility can be explained by prolonged spreading among humans (which wasn't observed, neither were intermediate strains) or e.g. lab experiments such as passaging with human cells.
4/x
MPXV22 rapid spread is highly unusual.
Increased transmissibility can be explained by prolonged spreading among humans (which wasn't observed, neither were intermediate strains) or e.g. lab experiments such as passaging with human cells.
4/x
3) NUMBER OF MUTATIONS
DNA viruses usually mutate very slowly, accumulating 1-2 mutations/year. This MPXV22 mutated 6-12x faster, which AFAIK has never before been observed in nature.
(sources of many following statements:
https://virological.org/t/discussion-of-on-going-mpxv-genome-sequencing/802
https://www.researchsquare.com/article/rs-1700947/v1)
5/x
DNA viruses usually mutate very slowly, accumulating 1-2 mutations/year. This MPXV22 mutated 6-12x faster, which AFAIK has never before been observed in nature.
(sources of many following statements:
https://virological.org/t/discussion-of-on-going-mpxv-genome-sequencing/802
https://www.researchsquare.com/article/rs-1700947/v1)
5/x
