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Shedding...
plausible process by which it could occur through the release of exosomes from dendritic cells in the spleen containing misfolded spike proteins, in complex with other prion reconformed proteins. These exosomes can travel to distant places. https://twitter.com/9KUSATHINKS/status/1484215543251017733
plausible process by which it could occur through the release of exosomes from dendritic cells in the spleen containing misfolded spike proteins, in complex with other prion reconformed proteins. These exosomes can travel to distant places. https://twitter.com/9KUSATHINKS/status/1484215543251017733
Through the release of exosomes from dendritic cells in the spleen containing misfolded spike proteins, in complex with other prion reconformed proteins. These exosomes can travel to distant places.
It is not impossible to imagine that they are being released from the lungs and inhaled by a nearby person.
Extracellular vesicles, including exosomes, have been detected in sputum, mucus, epithelial lining fluid, and bronchoalveolar lavage fluid in association with respiratory diseases (Lucchetti et al., 2021).
https://www.doi.org/10.1183/13993003.03024-2020
https://www.doi.org/10.1183/13993003.03024-2020
H/t @Clucky92864053
Studies that show that Spike protein ends up in exosomes which will then be consumed by phagocytes...
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00730-1 https://twitter.com/Clucky92864053/status/1484276379092987904
Studies that show that Spike protein ends up in exosomes which will then be consumed by phagocytes...
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00730-1 https://twitter.com/Clucky92864053/status/1484276379092987904
A Phase 1/2/3 study undertaken by BioNTech on the Pfizer mRNA vaccine implied in their study protocol that they anticipated the possibility of secondary exposure to the vaccine (BioNTech, 2020).
https://media.tghn.org/medialibrary/2020/11/C4591001_Clinical_Protocol_Nov2020_Pfizer_BioNTech.pdf
https://media.tghn.org/medialibrary/2020/11/C4591001_Clinical_Protocol_Nov2020_Pfizer_BioNTech.pdf
The protocol included the requirement that “exposure during pregnancy” should be reported by the study participants. They then gave examples of “environmental exposure during pregnancy” which included exposure “to the study intervention by inhalation or skin contact.”
They even suggested two levels of indirect exposure: “A male family member or healthcare provider who has been exposed to the study intervention by inhalation or skin contact then exposes his female partner
prior to or around the time of conception.”
prior to or around the time of conception.”
‘Leaky’ 
Can Produce Stronger Versions of Viruses
These less-than-perfects create a “leaky” barrier against the virus.
Can Produce Stronger Versions of Viruses These less-than-perfect
s create a “leaky” barrier against the virus.
ed individuals may get sick but have less severe symptoms, but the virus survives long enough to transmit to others, which allows it to survive and spread throughout a population.
Imperfect Vaccination Can Enhance the
Transmission of Highly Virulent Pathogens
But when vaccines leak, allowing at least some pathogen transmission, they could create the ecological conditions that would allow hot strains to emerge and persist.
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198
Transmission of Highly Virulent Pathogens
But when vaccines leak, allowing at least some pathogen transmission, they could create the ecological conditions that would allow hot strains to emerge and persist.
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198
Peron, J. P. S. & Nakaya, H. (2020). Susceptibility of the Elderly to SARS-CoV-2 Infection: ACE-2 Overexpression,
Shedding, and Antibody-dependent Enhancement (ADE). Clinics (Sao Paulo) 75: e1912.
https://www.scielo.br/j/clin/a/QDXYJBQk6YyLpfGNgBKtxHQ/?lang=en
Shedding, and Antibody-dependent Enhancement (ADE). Clinics (Sao Paulo) 75: e1912.
https://www.scielo.br/j/clin/a/QDXYJBQk6YyLpfGNgBKtxHQ/?lang=en
Johns Hopkins "Health Security" model: self amplifying/self spreading vax-eens https://www.medicdebate.org/taxonomy/term/4277
Self-amplifying mRNA vaccines https://pubmed.ncbi.nlm.nih.gov/25620012/
Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action https://pubmed.ncbi.nlm.nih.gov/33861374/
Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection https://pubmed.ncbi.nlm.nih.gov/32619745/
Self-amplifying RNA vaccines for infectious diseases https://www.nature.com/articles/s41434-020-00204-y
Self-disseminating vaccines for emerging infectious diseases https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4732410/
