Children are not just 'small adults.’ Biologically, they are going through anatomical, physiological, pathological, and immunological changes. Therefore, many drugs and vaccines may exhibit different pharmacokinetics than would be observed in an adult... https://www.nature.com/articles/d41586-021-01061-4

at all levels of drug disposition (absorption, distribution, metabolism, and excretion). For this reason, a COVID-19 vaccine approved for children under 16 is not yet available, but clinical trials are underway to unravel the COVID vaccine's effects specific to young children...

Major vaccine developers like @pfizer and @moderna_tx are running clinical trials to gain an understanding of how the COVID-19 vaccine will work in children, including neonates...

The US Food and Drug Administration ( @US_FDA) will carefully review all of the data from the trials to ensure they are safe and effective to be used in the pediatric population before granting an emergency use authorization (EUA) to any COVID-19 vaccine for kids...

Learn more about questions scientists will be asking throughout the clinical trials in the first tweet of this thread.

#COVID19 #VaccinesSaveLives #research