Thread by @amarkelkar, “neutralizing” Igs to SARS-CoV2 spike protein at median 29 days after 2nd [...]

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⏫" title="Nach oben zeigendes doppeltes Dreieck" aria-label="Emoji: Nach oben zeigendes doppeltes Dreieck">“neutralizing” Igs to SARS-CoV2 spike protein at median 29 days after 2nd mRNA vaccine dose (85%

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⏩" title="Nach rechts zeigendes doppeltes Dreieck" aria-label="Emoji: Nach rechts zeigendes doppeltes Dreieck">46% of 658 still w/o measurable Igs; 57% of 473 on IST). Low ORR!

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⚠️" title="Warnsignal" aria-label="Emoji: Warnsignal">Surrogate endpoint (protection

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤷🏽‍♂️" title="Achselzuckender Mann (mittlerer Hautton)" aria-label="Emoji: Achselzuckender Mann (mittlerer Hautton)">)

https://abs.twimg.com/emoji/v2/... draggable="false" alt="❓" title="Rotes Fragezeichen-Symbol" aria-label="Emoji: Rotes Fragezeichen-Symbol">When patients got their solid organ transplants

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🚨" title="Polizeiautos mit drehendem Licht" aria-label="Emoji: Polizeiautos mit drehendem Licht">Significance for HSCT? https://twitter.com/jama_current/status/1390124154884657153">https://twitter.com/jama_curr...

https://twitter.com/jama_current/status/1390124154884657153

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🌟" title="Leuchtender Stern" aria-label="Emoji: Leuchtender Stern"> @CIBMTR/ @BMTCTN ongoing prospective observational trial to assess durability of SARS-CoV2 vaccine response at 6 mo.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">includes patients ≤ 12 months from alloHCT, autoHCT, or CAR-T therapy

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧪" title="Test tube" aria-label="Emoji: Test tube"> @Labcorp SARS-CoV-2 Semi-Quantitative Total Antibody

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤷🏽‍♂️" title="Achselzuckender Mann (mittlerer Hautton)" aria-label="Emoji: Achselzuckender Mann (mittlerer Hautton)">now

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⁉️" title="Ausrufe-Fragezeichen" aria-label="Emoji: Ausrufe-Fragezeichen">
https://web.emmes.com/study/bmt2/protocol/2101_protocol/CIBMTR-07%20BMT%20CTN%202101_COVID%20Vaccine%20Study%20Plan_v2.0_20210416.pdf">https://web.emmes.com/study/bmt...

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🗺" title="Weltkarte" aria-label="Emoji: Weltkarte"> @ASH_hematology/ @ASTCT #COVID19Vaccine FAQs for HSCT/CAR-T recipients:

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Can offer vaccine ≥3 mo after HSCT

https://abs.twimg.com/emoji/v2/... draggable="false" alt="❓" title="Rotes Fragezeichen-Symbol" aria-label="Emoji: Rotes Fragezeichen-Symbol">Efficacy

https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤷🏽‍♂️" title="Achselzuckender Mann (mittlerer Hautton)" aria-label="Emoji: Achselzuckender Mann (mittlerer Hautton)">No preferred vaccine
≥14d b/w mRNA vaccine and other vaccines (COVID-19>routine vaccination)

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👎🏽" title="Daumen runter (mittlerer Hautton)" aria-label="Emoji: Daumen runter (mittlerer Hautton)">Vaccines for transplant candidates

https://www.hematology.org/covid-19/ash-astct-covid-19-vaccination-for-hct-and-car-t-cell-recipients">https://www.hematology.org/covid-19/...

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⏰" title="Wecker" aria-label="Emoji: Wecker">Delay vaccine ≥90 days if prior mAb or convalescent plasma

https://abs.twimg.com/emoji/v2/... draggable="false" alt="❌" title="Kreuzzeichen" aria-label="Emoji: Kreuzzeichen">testing with serology

https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Close contacts

https://abs.twimg.com/emoji/v2/... draggable="false" alt="⬆️" title="Pfeil nach oben" aria-label="Emoji: Pfeil nach oben">supply now, should vaccination start sooner than 90 days post-HSCT?
@mini_kamboj @ZainabShd @JoshuaHillMD @tmhohl71 @JeffAuletta @Zee81582915 @AbidiMaheen @alpanaw @PergamIC

Delay vaccine ≥90 days if prior mAb or convalescent plasmahttps://abs.twimg.com/emoji/v2/... draggable="false" alt="❌" title="Kreuzzeichen" aria-label="Emoji: Kreuzzeichen">testing with serologyhttps://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Close contactshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="⬆️" title="Pfeil nach oben" aria-label="Emoji: Pfeil nach oben">supply now, should vaccination start sooner than 90 days post-HSCT? @mini_kamboj @ZainabShd @JoshuaHillMD @tmhohl71 @JeffAuletta @Zee81582915 @AbidiMaheen @alpanaw @PergamIC" title="https://abs.twimg.com/emoji/v2/... draggable="false" alt="⏰" title="Wecker" aria-label="Emoji: Wecker">Delay vaccine ≥90 days if prior mAb or convalescent plasmahttps://abs.twimg.com/emoji/v2/... draggable="false" alt="❌" title="Kreuzzeichen" aria-label="Emoji: Kreuzzeichen">testing with serologyhttps://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Close contactshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="⬆️" title="Pfeil nach oben" aria-label="Emoji: Pfeil nach oben">supply now, should vaccination start sooner than 90 days post-HSCT? @mini_kamboj @ZainabShd @JoshuaHillMD @tmhohl71 @JeffAuletta @Zee81582915 @AbidiMaheen @alpanaw @PergamIC" class="img-responsive" style="max-width:100%;"/>

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