Buyer's remorse after dose #1 AZ? I get it. Don't feel bad. You weren't fooled, conned, cheated or bamboozled. You made the right decision to keep yourself & your community safe and I'll tell you why. 1/
Nobody can defend the woeful communications PR record of AZ when it comes to transparency of early trial dosing protocols or choice of how/when to release efficacy results. But this is truly an example of "great player, bad coach" 2/
AZ is 100% effective vs. serious disease, hospitalization or death. This sounds like a broken record but these are the most important metrics for safety & the ones that determine health care capacity, potential for licking this pandemic sooner! 3/
AZ was trialed in the UK during the emergence of B.1117, now the most dominant VOC in the world. It has been the cornerstone of UK vaccine rollout & is allowing safe easing of restrictions. This is what real world evidence means 4/
AZ is the ONLY vaccine with trial evidence for efficacy with extended dose intervals, demonstrating superior results with intervals of 12 weeks vs < 6 weeks. Not saying this should be done for everyone but it should at least offer some reassurance to many 5/
Finally, remember it was once inconceivable to expect timely approval of ANY vaccine that was accessible to most. Many people still don't have access. If you are fortunate enough, don't take it for granted. Take the vaccine instead. 6/ End
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