Buyer& #39;s remorse after dose #1 AZ? I get it. Don& #39;t feel bad. You weren& #39;t fooled, conned, cheated or bamboozled. You made the right decision to keep yourself & your community safe and I& #39;ll tell you why. 1/
Nobody can defend the woeful communications PR record of AZ when it comes to transparency of early trial dosing protocols or choice of how/when to release efficacy results. But this is truly an example of "great player, bad coach" 2/
AZ is 100% effective vs. serious disease, hospitalization or death. This sounds like a broken record but these are the most important metrics for safety & the ones that determine health care capacity, potential for licking this pandemic sooner! 3/
AZ was trialed in the UK during the emergence of B.1117, now the most dominant VOC in the world. It has been the cornerstone of UK vaccine rollout & is allowing safe easing of restrictions. This is what real world evidence means 4/
AZ is the ONLY vaccine with trial evidence for efficacy with extended dose intervals, demonstrating superior results with intervals of 12 weeks vs < 6 weeks. Not saying this should be done for everyone but it should at least offer some reassurance to many 5/