https://abs.twimg.com/emoji/v2/... draggable="false" alt="💥" title="Symbol für eine Kollision" aria-label="Emoji: Symbol für eine Kollision">https://abs.twimg.com/emoji/v2/... draggable="false" alt="💥" title="Symbol für eine Kollision" aria-label="Emoji: Symbol für eine Kollision">https://abs.twimg.com/emoji/v2/... draggable="false" alt="💥" title="Symbol für eine Kollision" aria-label="Emoji: Symbol für eine Kollision">https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Identification of the https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VIRAL ENVELOPE in SC2https://abs.twimg.com/emoji/v2/... draggable="false" alt="❗" title="Rotes Ausrufezeichen" aria-label="Emoji: Rotes Ausrufezeichen">https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">1) If we analyze the CD21480 file, of SARS CoV 2 Spike S1-RBD, we can understand how much the binding domain of the receptor of the S1 subunit, of the Spike (S) protein, contains a list of highly
2) pathogenic infectious agents.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> CoV S protein is an envelope glycoprotein that plays the most important role in viral attachment, fusion and entry into host cells and serves as a primary target for the development of neutralizing antibodies, viral entry inhibitors
3) and vaccines.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> It is synthesized as a precursor protein that is cleaved into an N-terminal S1 subunit (700 amino acids) and a C-terminal S2 subunit (600 amino acids) which mediates membrane attachment and fusion, respectively.
4) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Three S1 / S2 heterodimers assemble to form a trimer peak protruding from the viral envelope.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> The S1 subunit contains a receptor binding domain (RBD), while the S2 subunit contains a hydrophobic fusion peptide and two heptad repeat regions.
5) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> S1 contains two structurally independent domains, the N-terminal domain (NTD) and the C-terminal domain (domain C).

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Depending on the virus, the NTD or the C domain can act as a receptor binding domain (RBD).
6) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> While murine hepatitis virus (MHV) RBD is found in the NTD, most other CoVs, including SARS-CoV-2, use the C domain to bind their own receptors.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Recent studies have found that the receptor-binding domain (RBD) of the SC2-S protein binds strongly to human and bat
7) angiotensin-converting enzyme 2 (ACE2) receptors.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Furthermore, SARS-CoV-2 RBD showed significantly higher binding affinity for the ACE2 receptor than SARS-CoV RBD.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Due to the key role of the RBD protein S in viral attachment, it is the main target for
8) antibody-mediated neutralization.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Below, in this link, you can read the sequence alignment of SARS CoV 2 Spike S1-RBD:https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">

https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=394827

https://www.ncbi.nlm.nih.gov/Structure... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Continuing, through a comparative research, a document by Shi Z. emerged. =  ( https://www.nature.com/articles/s41586-020-2012-7">https://www.nature.com/articles/... )
A pneumonia outbreak associated with a new coronavirus of probable bat origin

Characterization of full-length genome sequences from patients infected with a new coronavirus (2019-nCoV) shows that the sequences are nearly identical and indicates that the virus is related to a...

https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=394827
9) in which the complete genomic sequence of the https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">WIV02 virus obtained from a patient is provided hit onhttps://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">December 30, 2019 and hospitalized athttps://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">Whuan Jihyintan hospital.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">The paper refers to the Gen Bank Archive,spike glycoprotein Severe acute respiratory
10) syndrome coronavirus 2:https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">

https://www.ncbi.nlm.nih.gov/protein/1807246650

https://www.ncbi.nlm.nih.gov/protein/1... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> In the paper by Shi Z., under the item Availability of data, you can read:https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Sequence data supporting the results of this study were filed in GISAID ( https://www.gisaid.org/ )">https://www.gisaid.org/">... with membership numbers
11) with membership numbers EPI_ISL_402124,
EPI_ISL_402127 - EPI_ISL_402130, and EPI_ISL_402131;
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">GenBank with access numbers MN996527 -
MN996532;
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Scienceshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten"> ( https://bigd.big.ac.cn/databases?lang=en)">https://bigd.big.ac.cn/databases...
12) with access numbers: SAMC133236 -
SAMC133240, and
SAMC133252.

(Insights: Shi Z. has carried out several projects, with https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">WIV02, from which new subsequent experiments with new WIV viruses are generated:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
  https://bigd.big.ac.cn/biosample/browse/SAMC133236
https://bigd.big.ac.cn/biosample... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://bigd.big.ac.cn/gsa/browse/CRA002423
https://bigd.big.ac.cn/gsa/brows... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
13) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten"> https://bigd.big.ac.cn/gsa/browse/CRA002423/CRX097477 )

https://bigd.big.ac.cn/gsa/brows... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> Let& #39;s take into consideration the access number to Gen Bank: https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">MN996527 (MN996532 instead belongs to the RaTG13 virus which is actually a "visual diversion", created to divert attention from the WIV virus family), in which you can read its
14) entire genomic sequence:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://www.ncbi.nlm.nih.gov/nuccore/MN996527

https://www.ncbi.nlm.nih.gov/nuccore/M... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> The virus WIV02: Severe acute respiratory syndrome coronavirus 2 isolate WIV02, complete genome, then refers to the following link:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://webcache.googleusercontent.com/search?q=cache:B84T821B7F8J:https://bigd.big.ac.cn/gwh/Assembly/952/show+&cd=1&hl=it&ct=clnk&gl=it">https://webcache.googleusercontent.com/search...
15) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
16) This intermediate link is very important because it provides a first cognitive approach to who created it and how it was developed:

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Scientific name Severe acute respiratory syndrome coronavirus 2

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Common name Bioproject PRJCA002163

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Biosample SAMC133236
17) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Membership n. GWHABKK00000000

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Raw GSA readings - Variations GVM16.114 (SNP),820 (Indel)

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Sender Organization https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">CAS Key Laboratory of Special Pathogens and Biosafety and Center for Emerging Infectious Diseases

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Wuhan Institute of Virology,Chinese Academy of Sciences
18) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Contact: Peng Zhou, peng.zhou@wh.iov.cn Sequence authors Peng Zhou, Xinglou Yang, Xianguang Wang, Lei Zhang, Yan Zhu, Haorui Si, Zhengli Shi.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Issued 01-30-2020

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Complete genome assembly level

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Representation of the genome Complete genome

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Reference genome, yes
19) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Geneious assembly method v11.0.3, Megahit v1.2.9

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Sequencing and coverage Illumina MiSeq 74862.73271, MGISEQ 2000 6.747680972E9

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Finally WIV02 then refers to Wuhan-Hu-1, where you can read, in Gen Bank, the entire sequence:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://www.ncbi.nlm.nih.gov/nucleotide/MN908947">https://www.ncbi.nlm.nih.gov/nucleotid...
20) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">And it is here, in this link, that you can go back, in a direct and precise way, to obtaining the viral envelope of SC2 and its incredible list of highly pathogenic infectious agents:
21) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://www.viprbrc.org/brc/viprDetails.spg?ncbiProteinId=QHD43416&decorator=corona

https://www.viprbrc.org/brc/viprD... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">I attach the graphic scheme consisting of the entire genomic sequence, of Wuhan-Hu-1, with its double amino acid / protein codon.
22) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Scrolling through the list of various items, you get to the item, Gene Composition, where under the item: Cellular Component you can read: https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VIRAL ENVELOPE.
22) https://abs.twimg.com/emoji/v2/... draggable=Scrolling through the list of various items, you get to the item, Gene Composition, where under the item: Cellular Component you can read: https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VIRAL ENVELOPE." title="22) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Scrolling through the list of various items, you get to the item, Gene Composition, where under the item: Cellular Component you can read: https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VIRAL ENVELOPE." class="img-responsive" style="max-width:100%;"/>
23)
24) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
25) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Thanks to the code of the viral envelope: 0019031, it was possible to trace the exact composition of the pathogens present in Viral Enveloped (N), of SC2:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://www.ebi.ac.uk/QuickGO/term/GO:0019031 

https://www.ebi.ac.uk/QuickGO/t... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">This link is a “mine” of information, disconcerting and incredible, which I have named
26) "Aladdin& #39;s Cave", it is the "Secretum Secretorum" of the chimeric virus SC2 where it is listed, one by one, all the infectious pathogens present in large quantity, both in S1 and in N.
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
26) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
27) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
28) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> In addition to the already disconcerting viral envelope belonging to N, it was also possible to trace the exact composition of the pathogens present in the trimerium S1, S2, of SC2, thanks to this sub-link:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
https://www.ebi.ac.uk/QuickGO/term/GO:0044423
https://www.ebi.ac.uk/QuickGO/t... class="Emoji" style="height:16px;" src=" https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
In the viral envelope: https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">0044423,
29) Virion Component, you can read the viral composition of S1 / Spike:https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
30) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten">
31) https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">CONCLUSIONS / CONSIDERATIONS,PATHOGENS COMPONENTS IN THE VIRAL ENVELOPE.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">INFLUENCE A/B/C=The co-presence of all three influenza viruses explains how they have been skilfully used,under the radar,by SC2;forming a highly infectious pelvis,especially in frail and elderly
32) people.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">FLAVIVIRUS NS4A / NS2B = ssRNA positive single-stranded RNA virus, belonging to the Flaviviridae family. They result in a variety of different diseases with fever, sometimes severe encephalitis and / or hemorrhagic fever. Dengue virus, Zika, and
33) yellow fever also belong to this family. The Flaviivrus virus is divided into 2 clades: the first is given by viruses transmitted by a vector and while the second clade is given by viruses without the known vector. The vector clade, in turn, can be divided into a
34) mosquito-borne clade and a tick-borne clade. The mosquito group can be divided into two branches: one branch contains neurotropic viruses, often associated with encephalitic disease in humans or livestock. The second branch is given by non-neurotropic viruses
35) associated with haemorrhagic disease in humans and primates.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">PNEUMOVIRUS = RNA negative single-stranded virus, belonging to the order Mononegavirales, family Pneumoviridae. The type species is the human respiratory syncytial virus, an important causative
36) agent of both infantile bronchiolitis and pneumonia.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">ARENAVIRUS = RNA virus, ambisense, which infects rodents and occasionally humans. Arenaviruses cause human disease and vary in severity. Aseptic meningitis, a serious human disease that causes
37) inflammation that covers the brain and spinal cord, can result from the lymphocytic choriomeningitis virus. Hemorrhagic fever syndromes, including Lassa fever, are derived from infections such as Guanarito virus, Junin virus, Lassa virus, Lujo
38) virus, Machupo virus, Sabia virus, or Whitewater Arroyo virus. Glycoprotein (GP) is synthesized as a precursor molecule. It is divided into three parts: GP1, GP2 and a stable signal peptide (SSP). These reactions are catalyzed by cell signal peptidases and the
39) cellular enzyme Subtilisin Kexin Isozyme-1 (SKI-1) / Site-1 in Protease (S1P). These processes are essential for fusion competence and the incorporation of mature GP into nascent virion particles.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">PARAMIXOVIRUS = have a single-stranded RNA. Parainfluenza viruses, mumps
40) virus, measles virus and human respiratory syncytial virus belong to this family.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">HIV Gp120 = Gp120 is a viral glycoprotein present in the pericapsid of the HIV virus, It is an essential protein for the entry of the virus into cells, it plays a
41) fundamental role in cell adhesion through receptors of the DC-SIGN type, heparan sulfate and a specific interaction with CD4 of helper T lymphocytes.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">EIAV Gp90 / Gp2b = equine infectious anemia, classified in the family Retroviridae, in the
42) subfamily Lentivirinae (which also includes the sheep Visna-maedi viruses, arthritis - caprine encephalitis, and the viruses responsible for the infection of humans, monkeys, felines and bovine immunodeficiency) .

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">HEPATITE C = HCV belongs to the hepacivirus genus in the
43) Flaviviridae family and primarily affects the liver. Co-infection with HIV is very common.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">HERPESVIRUS = Herpes simplex virus (Varicella-zoster virus); latency site: nerve endings of the CNS. Characteristic of this family of viruses is that it no
44) longer leaves the host after the first infection and nestles in a cell type of the organism, causing a so-called latent infection. This family is also linked to the Epstein-Barr virus; its seat of latency lies in the lymphoid cells.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">CITOMEGALOVIRUS = The
45) genus includes viruses that infect various species of primates, including humans. The two cases in which serious complications can occur are the pregnant patient and the immunocompromised patient. The latter, for example, can undergo chorioretinitis,
46) esophagitis, hepatitis and, especially for reactivation of the virus from the latency phase, encephalitis and pneumonia.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">ARTERIVIRUS Cp4 = These proteins, collectively referred to as "replicase / transcriptase" or, for simplicity, simply "replicase", are
47) encoded by open read frames 1a and 1b (ORF1a and ORF1b) of the arterivirus genome. Furthermore, the family includes viruses of veterinary interest with high genomic variability, capable of causing persistent infections with prolonged viremia and the ability to replicate in
48) macrophages. (It is no coincidence that this virus is always found in laboratory experiments carried out with animals in vivo).

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">CHORDOPOXVIRUS = This is a Chordopoxvirinae family of viral fusion proteins. A Vaccinia virus protein has been shown to
49) function as a viral fusion protein that mediates cell fusion.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">PROXVIRUS P35 / Ag35 / A14 / A28 = The smallpox and alastrim viruses also belonged to this family, diseases that have now been eradicated, but still strangely present in the viral envelope of SC2.
50) https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">BACULOVIRUS Gp64 / E56 / E66 / E25 / EC27 / E18 = The envelope fusion protein GP64 is an essential baculovirus protein required for cell-to-cell infection transmission. Baculoviruses infect insects (such as mosquitoes, linked to malaria), with over 600
51) host species. In the 1940s, baculovirus was widely used and studied as a biopesticide in cultivated fields. Since the 1990s they have been used to produce complex eukaryotic proteins in insect cell cultures (Sf21, High Five cells). These recombinant proteins have been used in
52) research and as vaccines in both human and veterinary medical treatments (e.g., the most widely used vaccine for the prevention of H5N1, avian influenza in chickens that has been produced in a baculovirus expression vector ). More recently it has been discovered that
53) baculoviruses can also be transduced into mammalian cells, through the use of VLP / Sf21 particles suspended in a yeast culture inside which mammalian cells are present.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">CORE Gp120 = Gp120 is a viral glycoprotein present in the pericapsid of the HIV virus. It is an
54) essential protein for the entry of the virus into cells, it plays a fundamental role in cell adhesion via DC-SIGN type receptors, heparan sulfate and a specific interaction with CD4 of helper T lymphocytes.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">RHABDOVIRUS = Bats are carriers of the Lyssavirus, or
55) rabies virus, which is responsible for rabies and vesicular stomatitis in cattle and horses. The viral particle is wrapped in a fatty membrane; it is shaped like a “bullet” (70 by 180 nm) and contains a single helical strand of ribonucleic acid (RNA).
56) The pathogen of rabies is a Lyssavirus with different genotypes; Genotype 1 is the classic rabies virus that can also cause vesicular stomatitis.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VSV MATRIX = The vesiculovirus matrix protein family consists of several matrix proteins of the vesicular
57) stomatitis virus, also known as VSIV or VSV. The matrix (M) protein of the virus causes many of the cytopathic effects of VSV, the M protein also induces apoptosis (cell death). These proteins play an important role in the assembly and budding of VSIV
58) virions. Their main role is to help assemble the virus. They begin by disrupting host cell transcription by inhibiting nuclear export of mRNA through direct interaction with the host& #39;s RAE1 -NUP98 complex. This inhibits the signaling of interferon and thus
59) the creation of an antiviral state in virus-infected cells. In turn, this induces cell rounding, disorganization of the cytoskeleton and apoptosis in the infected cell.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">VESICULOVIRUS = As with RHABDOVIRUS, this virus is linked to the rabies virus, it also causes
60) vesicular stomatitis.

https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉" title="Rückhand Zeigefinger nach rechts" aria-label="Emoji: Rückhand Zeigefinger nach rechts">TROMBUSVIRUS P19 = RNA silencing suppressor p19 (also known as the Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed by the ORF4 gene in the tombusvirus genome. The p19 protein acts as a counter-defense
61) strategy, specifically binding 19 to 21 nucleotide double-stranded RNAs that function as small interfering RNAs (siRNAs) in the RNA silencing system. By sequestrating siRNA, p19 suppresses RNA silencing and promotes viral proliferation. By binding to siRNA, p19
62) sequestrates these species and prevents them from interacting with the RNA-induced silencing complex (RISC), a protein complex that mediates the antiviral RNA silencing mechanism in the cell.
63)https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts"> FINAL:

All these pathogens, now well identified in the Viral Envelope of SC2, have similar and almost always recurring correspondences, which unite them all, as if they belonged to a cleverly studied viral project, with a very specific purpose.
64) The pharmacological response in medical protocols, in response to SC2, should be very high but, on the contrary, there have been deficiencies in the use of unsuitable drugs, increasing lethality in the population.

For example, it is no coincidence
that the understanding of the mechanism of action of bacterial lysates (specialties of medicines that contain bacterial antigens, i.e. fragments of bacteria, or polypeptide chains which, if taken by a healthy organism, should stimulate its immune response )
is the main cause of relapse in severe respiratory infections, such as acute pneumonia, and therefore its use should be prohibited.

In fact, inside the lysates there are endogenous microsomes with an active translocon complex (such as vesicular cellular artifacts
derived from the fragmentation of the endoplasmic reticulum in the laboratory) which facilitate the incorporation of the bacterial channel of potassium KcsA (ion channels that allow the passage of cations of potassium through the plasma membrane of the
cells), within the microsomal membranes themselves.

This would explain very well how, after the appearance of SC2, there was an exponential increase in the number of bacterial strains resistant to antibiotics, especially Gram negative.
SC2, due to its zoonotic / chimeric origin and its "parasitic nature", in addition to creating a very serious syndrome, which attacks both the vascular system and the immune system, binds and spreads mainly through bacterial, intestinal and external colonies to the guest.
For this reason, precisely due to the presence of the Viral Envelope present in SC2, all immunological control strategies of infectious diseases should be re-evaluated instantly.
(End)
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