It was great to be with all of my friends at @ACPinternists today at #ACP2021! I gave the #UpdatesInGI talk, so want to summarize the 7 papers here! These are what YOU, my #GITwitter and #MedTwitter friends, helped identify as the top papers for the last year....
Paper 1:
Not all “GERD” = #GERD. @AGA_CGH
Who may benefit from PPIs most?
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Esophagitis
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Barrett’s
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Heartburn w/ or w/o esophagitis
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Regurg w/ or w/o esophagitis
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Chest pain w/objective GERD
https://abs.twimg.com/emoji/v2/... draggable="false" alt="➡️" title="Pfeil nach rechts" aria-label="Emoji: Pfeil nach rechts">Cough w/objective GERD
The rest
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤷🏻♀️" title="Achselzuckende Frau (heller Hautton)" aria-label="Emoji: Achselzuckende Frau (heller Hautton)"> or
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🚫" title=""Betreten verboten!"-Zeichen" aria-label="Emoji: "Betreten verboten!"-Zeichen">
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960363/">https://www.ncbi.nlm.nih.gov/pmc/artic...
Not all “GERD” = #GERD. @AGA_CGH
Who may benefit from PPIs most?
The rest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960363/">https://www.ncbi.nlm.nih.gov/pmc/artic...
Paper 2:
PPIs for persistent throat sxs?
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🚫" title=""Betreten verboten!"-Zeichen" aria-label="Emoji: "Betreten verboten!"-Zeichen">
In R-DB-PCT trial:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉🏼" title="Rückhand Zeigefinger nach rechts (mittelheller Hautton)" aria-label="Emoji: Rückhand Zeigefinger nach rechts (mittelheller Hautton)">346 pts w/persistent throat sxs
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉🏼" title="Rückhand Zeigefinger nach rechts (mittelheller Hautton)" aria-label="Emoji: Rückhand Zeigefinger nach rechts (mittelheller Hautton)">Lansoprazole 30 BID x16 wks vs placebo
https://abs.twimg.com/emoji/v2/... draggable="false" alt="👉🏼" title="Rückhand Zeigefinger nach rechts (mittelheller Hautton)" aria-label="Emoji: Rückhand Zeigefinger nach rechts (mittelheller Hautton)">Outcome: rsp at 16 wks w/reflux sx index (RSI)
FINDING: No statistical difference in RSI b/t the groups.
https://www.bmj.com/content/bmj/372/bmj.m4903.full.pdf">https://www.bmj.com/content/b...
PPIs for persistent throat sxs?
In R-DB-PCT trial:
FINDING: No statistical difference in RSI b/t the groups.
https://www.bmj.com/content/bmj/372/bmj.m4903.full.pdf">https://www.bmj.com/content/b...
Paper 3:
New @AmCollegeGastro #ColorectalCancerScreening Guidelines
A few key points:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔑" title="Schlüssel" aria-label="Emoji: Schlüssel">CRC screening to start at age 45 for average-risk
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔑" title="Schlüssel" aria-label="Emoji: Schlüssel">Colonoscopy and FIT recommended as primary modalities
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔑" title="Schlüssel" aria-label="Emoji: Schlüssel">Quality metrics of endoscopists part of guidelines!
https://journals.lww.com/ajg/fulltext/2021/03000/acg_clinical_guidelines__colorectal_cancer.14.aspx">https://journals.lww.com/ajg/fullt...
New @AmCollegeGastro #ColorectalCancerScreening Guidelines
A few key points:
https://journals.lww.com/ajg/fulltext/2021/03000/acg_clinical_guidelines__colorectal_cancer.14.aspx">https://journals.lww.com/ajg/fullt...
Paper 4:
Now that colonoscopy done, polyps found, what next?
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤷🏻♀️" title="Achselzuckende Frau (heller Hautton)" aria-label="Emoji: Achselzuckende Frau (heller Hautton)">
USMSTF has updated recs for f/u after polypectomy!
Take-home points:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="⭐️" title="Mittelgroßer Stern" aria-label="Emoji: Mittelgroßer Stern">First ensure high quality colonoscopy (complete, prep ok, skilled endoscopists
https://abs.twimg.com/emoji/v2/... draggable="false" alt="⭐️" title="Mittelgroßer Stern" aria-label="Emoji: Mittelgroßer Stern">1-2 adenomas < 10 mm = 7-10 yrs!
https://www.gastrojournal.org/action/showPdf?pii=S0016-5085%2819%2941479-0">https://www.gastrojournal.org/action/sh...
Now that colonoscopy done, polyps found, what next?
USMSTF has updated recs for f/u after polypectomy!
Take-home points:
https://www.gastrojournal.org/action/showPdf?pii=S0016-5085%2819%2941479-0">https://www.gastrojournal.org/action/sh...
Paper 5:
PIANO
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🎹" title="Musik-Tastatur" aria-label="Emoji: Musik-Tastatur"> study looking at pregnancy and neonatal outcomes in women with #IBD on #Biologics and #Thiopurines
No increase in:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤰" title="Schwangere Frau" aria-label="Emoji: Schwangere Frau">Congenital malformations
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤰" title="Schwangere Frau" aria-label="Emoji: Schwangere Frau">Spontaneous abortions
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤰" title="Schwangere Frau" aria-label="Emoji: Schwangere Frau">Preterm birth
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤰" title="Schwangere Frau" aria-label="Emoji: Schwangere Frau">Low birth weight
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤰" title="Schwangere Frau" aria-label="Emoji: Schwangere Frau">Milestones
https://www.gastrojournal.org/action/showPdf?pii=S0016-5085%2820%2935441-X">https://www.gastrojournal.org/action/sh...
PIANO
No increase in:
https://www.gastrojournal.org/action/showPdf?pii=S0016-5085%2820%2935441-X">https://www.gastrojournal.org/action/sh...