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There’s a curious correlation between countries/regions of high prior SARS2 exposure and a resurgence upon the start of mass V immunization programs. I’ve been thinking a lot about this lately, and the only explanation that could fit observations is… 1/ https://www.bmj.com/content/372/bmj.n854
reactivation of dormant viruses in the population. (Seasonal) respiratory viral dormancy has been debated a lot for decades, but there’s still no consensus on where exactly these virions could lay dormant in the body, nor on the trigger(s) & mechanism(s) responsible for… 2/
reactivation. In light of recent research, my (educated?) guess is that the small intestine, and associated immune structures, is more likely place for this to occur than the respiratory tract. Admittedly, this is speculative, but neither implausible nor could I come up with… 3/
an explanation that better fits what’s seen in more and more countries.
Initially, I thought that poorly organized vaccination campaigns and careless behavior of vaccinated might explain the phenomenon, but it’s been becoming clear that this cannot be the case.
➟ #dormancy
4/4
Initially, I thought that poorly organized vaccination campaigns and careless behavior of vaccinated might explain the phenomenon, but it’s been becoming clear that this cannot be the case.
➟ #dormancy
4/4
I’ll keep amending this mini-thread with (potentially) supporting evidence.
Just as infection with other viruses, vaccination can also reactivate e.g. shingles. https://gizmodo.com/what-to-know-about-the-study-linking-covid-19-vaccines-1846723496
Just as infection with other viruses, vaccination can also reactivate e.g. shingles. https://gizmodo.com/what-to-know-about-the-study-linking-covid-19-vaccines-1846723496
Immunosuppressive states are also known to result in reactivation of dormant viruses. Space travel is one such example. The week (or so) following a strongly immunogenic systemic vaccination is also immunosuppressive. https://www.popsci.com/spaceflight-reactivate-dormant-herpes-virus/
Adding this case report here. Thanks for sharing. https://twitter.com/lairdwd2/status/1387418601464942599
Evidence for viral dormancy at least up to 6 months. https://twitter.com/gerdosi/status/1381238185464889345
