Ann Ginsberg reminds us that ‘improved TB vaccines are feasible& #39; as she gave a quick overview of the pipeline & candidates to be discussed today:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">M72/AS01E ( @gatesfoundation)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">DAR-901 ( @GeiselMed)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">MTBVAC ( @zendalgroup)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">H56:IC31 ( @ssi_dk)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">VPM1002 ( @SerumInstIndia) (1/?) https://twitter.com/GlobForumTBVax/status/1384850918223536130">https://twitter.com/GlobForum...
Ann Ginsberg reminds us that ‘improved TB vaccines are feasible& #39; as she gave a quick overview of the pipeline & candidates to be discussed today:https://abs.twimg.com/emoji/v2/... draggable=M72/AS01E ( @gatesfoundation)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">DAR-901 ( @GeiselMed)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">MTBVAC ( @zendalgroup)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">H56:IC31 ( @ssi_dk)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">VPM1002 ( @SerumInstIndia) (1/?) https://twitter.com/GlobForum..." title="Ann Ginsberg reminds us that ‘improved TB vaccines are feasible& #39; as she gave a quick overview of the pipeline & candidates to be discussed today:https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">M72/AS01E ( @gatesfoundation)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">DAR-901 ( @GeiselMed)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">MTBVAC ( @zendalgroup)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">H56:IC31 ( @ssi_dk)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">VPM1002 ( @SerumInstIndia) (1/?) https://twitter.com/GlobForum..." class="img-responsive" style="max-width:100%;"/>
Alexander Schmidt ( @gatesfoundation) provided an in-depth overview of M72/AS01E, inc. the multiple trials underway to assess the candidate & the need of candidate correlates of protection to accelerate #vaccine development. (2/?)
Ingrid Murillo Jelsbak gave a roundup of the #MTBVAC trials:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1a in adults (safer than BCG)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b in neonates (safer than BCG)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 2a in neonates & TB-infected &-uninfected adults (underway)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b/2a in adults & adolescents (underway)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 3 in neonates (TBD) (4/?)
Ingrid Murillo Jelsbak gave a roundup of the   #MTBVAC trials:https://abs.twimg.com/emoji/v2/... draggable=Ph. 1a in adults (safer than BCG)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b in neonates (safer than BCG) https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 2a in neonates & TB-infected &-uninfected adults (underway)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b/2a in adults & adolescents (underway)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 3 in neonates (TBD) (4/?)" title="Ingrid Murillo Jelsbak gave a roundup of the #MTBVAC trials:https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1a in adults (safer than BCG)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b in neonates (safer than BCG) https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 2a in neonates & TB-infected &-uninfected adults (underway)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 1b/2a in adults & adolescents (underway)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Ph. 3 in neonates (TBD) (4/?)" class="img-responsive" style="max-width:100%;"/>
Ingrid also shared recent data that demonstrated #MTBVAC offered significant protection compared to BCG in a model of respiratory #TB in rhesus macaques. The immune responses seen in the macaques reflect those identified in human clinical trials of MTBVAC. (5/?)
Alvaro Borges ( @ssi_dk) up next on H56:ICI31:
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">5 trials w/156 participants
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Showed safety & immunogenicity in TB-infected & -uninfected participants
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Phase 2b underway w/ major #COVID19 delays (results expected Q1 2024)
https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Aims for Prevention of Recurrence (POR) trial (6/?)
Alvaro Borges ( @ssi_dk) up next on H56:ICI31:https://abs.twimg.com/emoji/v2/... draggable=5 trials w/156 participantshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Showed safety & immunogenicity in TB-infected & -uninfected participants https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Phase 2b underway w/ major #COVID19 delays (results expected Q1 2024)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Aims for Prevention of Recurrence (POR) trial (6/?)" title="Alvaro Borges ( @ssi_dk) up next on H56:ICI31:https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">5 trials w/156 participantshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Showed safety & immunogenicity in TB-infected & -uninfected participants https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Phase 2b underway w/ major #COVID19 delays (results expected Q1 2024)https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">Aims for Prevention of Recurrence (POR) trial (6/?)" class="img-responsive" style="max-width:100%;"/>
Sajjad further showed applications for VPM1002 beyond TB, with an upcoming Ph.3: SARS-CoV-2 to assess VPM1002 in reducing hospital admissions &/or severe respiratory infectious diseases in elderly in #COVID19 pandemic in Germany (8/?)
Anastasia Koch led w/the call that public engagement is an essential science. Anastasia co-founded @Eh_woza, an NGO that produces youth-driven media to raises awareness about TB, infectious diseases, & South African biomedical research. (9/?)
In closing, Cheleka Anne-Marie Mpande spoke of how @Eh_woza engages w/community members in Khayelitsha w/representation as a central tenet. They recently ran surveys to inform Eh!Woza’s strategy, inc questions on where people access health info & their trust in #vaccines. (10/10)
You can follow @GlobForumTBVax.
Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled: