Do you find yourself learning a lot about anti-PF4 ELISA tests recently? @connors_md doing a great job breaking it down so we all can understand how this applies to VITT! @CDCgov

The result of this test (optical density, OD) is usually 0.5-2.0 for HIT. With VITT it seems to be >3.0!!

. @connors_md outlines the key steps in diagnosis. Vaccine exposure (AZ or JJ) in 5-24 day window is key! Get CBC and imaging test along with PF4 ELISA test. Don’t wait for ELISA result to start treatment!

. @Lbkreuziger takes over to cover VITT treatment.

Treatment options range from argatroban (for higher risk) to DOACs (for lower risk). Avoid heparin products and VKA