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Dr. Klimas’ #MECFS treatment recommendations, part of her #LongCovid presentation today to Body Politic #longhaulers organization.
Link to watch her talk (this slide starts at 56:36):
Link to watch her talk (this slide starts at 56:36):
She mentions that the herb Bacopa can affect oxidative stress in the brain, which is a new one for me!
She says that less than half of her MCAS patients don’t test positive, but she’s convinced this is the correct diagnosis. Calls mast cells “touchy little devils” because they trigger and leak a lot, ha! 
Dr. Klimas said that the idea that ppl w #MECFS won’t get better after 2-3 years of the disease is BOGUS. It’s a MADE UP/inaccurate conclusion based on a study of cytokine profiling. She said this is NOT her clinical experience, she’s seen some ppl get better after 20-30 yrs!
She says to watch NIH/Gov #LongCovid research funding like a HAWK so it doesn’t go to things it wasn’t intended for- be LOUD advocates about that! And that funding should go to #MECFS research- she’s worried about it not, & about researchers not referencing existing ME knowledge!
Her goal is to CURE MECFS, even in ppl who have been sick a long time.
Her team is about to start a phase 1 trial on treatments for #MECFS in people! Exciting! Hormones play a HUGE role in the disease so there are diff models for women, men, and post-menopausal women w MECFS
Her team is about to start a phase 1 trial on treatments for #MECFS in people! Exciting! Hormones play a HUGE role in the disease so there are diff models for women, men, and post-menopausal women w MECFS
Her team has successfully developed an animal model for #Gulfwarillness, and then CURED those mice!
WOW.
She said that #GWI has similar long-term sequelae as #MECFS but occurs from a different brain injury. Talks about this around min 44:16
WOW.
She said that #GWI has similar long-term sequelae as #MECFS but occurs from a different brain injury. Talks about this around min 44:16
Other cool & handy tidbits: Theres a current/ongoing study of MECFS patients at Cornell finding that 900mg of NAC 2x a day in ppl w #MECFS is NORMALIZING antioxidant levels in the brain.
Also, she recommends 4g daily (a lot!) of omega 3 for anti-inflammatory effects.
Also, she recommends 4g daily (a lot!) of omega 3 for anti-inflammatory effects.
In #MECFS , the immune system, neuroendocrine system (hormones!), & autonomic nervous system are dysfunctional, & the *Homeostasis* btwn them is off! That’s a key part of treatment & illness models
Also, the immune system is less good at keeping viruses from reactivating
Also, the immune system is less good at keeping viruses from reactivating
