Read on Twitter
1. Reporting 6 cases of cerebral venous sinus thrombosis plus low platelets- the same complication observed w/ AstraZeneca - among 7 million doses administered.
**If real, it would never have been picked up by clinical trials. The rate is TINY. No trial involves millions of ppl.
**If real, it would never have been picked up by clinical trials. The rate is TINY. No trial involves millions of ppl.
2. What makes it plausible?
the same complication has been reported as a very rare SE of AZ
these 2 vaccines have the same “vector” (adenovirus) https://www.gavi.org/vaccineswork/what-blood-clotting-disorder-astrazeneca-vaccine-has-been-linked
the same complication has been reported as a very rare SE of AZ these 2 vaccines have the same “vector” (adenovirus) https://www.gavi.org/vaccineswork/what-blood-clotting-disorder-astrazeneca-vaccine-has-been-linked
3. Even if real, let’s put it in context: if you catch #COVID19 you have an approximate 20% chance of getting a blood clot, according to a recent systematic review. (The real rate may be a little lower.)
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30383-7/fulltext
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30383-7/fulltext
4. Let’s compare: Which is higher?
5. Science and medicine, like life, is full of weighing risks vs benefits.
Right now, the risk of catching #covid19 & getting a bad complication is much higher than this very rare adverse effect.
BUT - for some groups (women? Young women?) that assumption may not be true.
Right now, the risk of catching #covid19 & getting a bad complication is much higher than this very rare adverse effect.
BUT - for some groups (women? Young women?) that assumption may not be true.
6. What is INDUBITABLY true right now is that #covid19 cases are rising in the US and across the world, and the J&J vaccine is very very good at preventing disease / excellent at preventing severe disease and death.
7. What is also true is that it is difficult for most of us to accurately judge risk of Omission (risk of avoiding vaccines) versus risk of commission (risk of getting vaccines).
We over estimate the latter, to our own - and our community’s - peril.
We over estimate the latter, to our own - and our community’s - peril.
8. There's also this: https://twitter.com/MaxKennerly/status/1381949175756099591?s=20
