As an example of how human brains don't personally grapple with risk well. There's a thing called micromorts - a one in a million chance of death. AZ has about 1.5 in a system like Australia - but here are some other activity micromorts from the ABS Causes of Death series....
About the same risk as dying from falling out of a chair (1.4 micromorts)

As likely to die in a building fire (1.6 micromorts)

Nearly twice as much risk of dying from falling out of bed. (2.8 micromorts)
Much more likely to get killed as a pedestrian (8.4 micromorts)

Plain old falling over is comparatively gigantic (17 micromorts)
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