Immunological memory consists of antibodies, memory B-cells, memory CD8+ T-cells, and memory CD4+ T-cells. These responses are what give us enduring protection even against newly emerging SARS-CoV-2 variants.

Immunological memory is probably the most important feature of immunity as it allows us to better respond when the threat is encountered a second time. Against SARS-CoV-2, it helps to determine protection against reinfection, disease risk, and vaccine efficacy.

As long as your T-cells still recognize this virus and inform your B-cells they need to get to work and adjust to make antibodies to be better “fit” you’re protected. Imagine your B-cells are your sword that need sharpening every now and again and your T-cells are your shield.