https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧶" title="Yarn" aria-label="Emoji: Yarn">02:

Vaccines (general)
My experience in 2021 with the Pfizer/BioNTec vaccination.

Should translate to English well automatically: https://twitter.com/Boschs_Owl/status/1347436664302555138?s=20">https://twitter.com/Boschs_Ow...
@podehaye‘s excellent thread about his experience w/ an Oxford vaccine trial: https://twitter.com/podehaye/status/1344474059392778240?s=20">https://twitter.com/podehaye/...
Article explaining viral vector vaccines in great detail: https://smw.ch/article/doi/smw.2017.14465">https://smw.ch/article/d...
Virally vectored vaccine delivery: medical needs, mechanisms, advantages and challenges

Contemporary vaccine makers are confronted with numerous challenging indications, for which virally vectored vaccines represent strong development candidates.

https://smw.ch/article/doi/smw.2017.14465
Politics.. https://twitter.com/Boschs_Owl/status/1354577163169779713?s=20">https://twitter.com/Boschs_Ow...
V01/02/03 - Dr. Faucis update https://twitter.com/Laurie_Garrett/status/1354497320289710086?s=20">https://twitter.com/Laurie_Ga...
https://twitter.com/angie_rasmussen/status/1354906659387187201?s=20">https://twitter.com/angie_ras...
https://twitter.com/TheGazmanRants/status/1355495906800508933?s=20">https://twitter.com/TheGazman...
https://twitter.com/kakape/status/1358821505203847169?s=20">https://twitter.com/kakape/st...
A long thread, more of a bookmark - but it gets interesting as a person who took part in an earlier ChAdOx-trial joined. https://twitter.com/Boschs_Owl/status/1354370391653961728?s=20">https://twitter.com/Boschs_Ow...
https://twitter.com/florian_krammer/status/1367198117368647693?s=20">https://twitter.com/florian_k...
https://twitter.com/_b_meyer/status/1369181719706865665?s=20">https://twitter.com/_b_meyer/...
https://twitter.com/itosettiMD_MBA/status/1370097879214395398?s=20">https://twitter.com/itosettiM...
https://twitter.com/SamWangPhD/status/1371658067763421185?s=20">https://twitter.com/SamWangPh...
https://twitter.com/quarkswdr/status/1372246514521808905?s=20">https://twitter.com/quarkswdr...
https://twitter.com/Volksverpetzer/status/1372492941869125639?s=20">https://twitter.com/Volksverp...
As a matter of fact it’s a lottery - that’s why I posted this here: https://twitter.com/EricTopol/status/1373313065714741249?s=20">https://twitter.com/EricTopol...
https://twitter.com/ajitjohnson_n/status/1364658526669398032?s=20">https://twitter.com/ajitjohns...
https://twitter.com/C_Mellenthin/status/1373906180289015811?s=20">https://twitter.com/C_Mellent...
https://twitter.com/bmj_latest/status/1374025606598381570?s=20">https://twitter.com/bmj_lates...
HK Govt:

Sinovac 62% efficacy at most (!)

https://www.fhb.gov.hk/download/our_work/health/201200/e_evaluation_report_CoronaVac.pdf">https://www.fhb.gov.hk/download/...
NIH: AstraZeneca asked if outdated data included https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤨" title="Gesicht mit hochgezogener Augenbraue" aria-label="Emoji: Gesicht mit hochgezogener Augenbraue"> https://www.nih.gov/news-events/news-releases/niaid-statement-astrazeneca-vaccine">https://www.nih.gov/news-even...
NIAID Statement on AstraZeneca Vaccine

Late Monday, the Data and Safety Monitoring Board (DSMB) notified NIAID, BARDA, and AstraZeneca that it was concerned by information released by AstraZeneca on initial data from its COVID-19 vaccine

https://www.nih.gov/news-events/news-releases/niaid-statement-astrazeneca-vaccine
via @abergthaler https://www.nature.com/articles/s41586-021-03412-7">https://www.nature.com/articles/...
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

https://www.nature.com/articles/s41586-021-03412-7
https://twitter.com/florian_krammer/status/1361020160333783045?s=20">https://twitter.com/florian_k...
https://twitter.com/CarlosdelRio7/status/1376902912908091392?s=20">https://twitter.com/Carlosdel...
https://twitter.com/ProMED_mail/status/1377782248259383296?s=20">https://twitter.com/ProMED_ma...
Via @profshanecrotty

6 Months milestone, fantastic news

https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-confirm-high-efficacy-and-no-serious">https://www.pfizer.com/news/pres...
https://twitter.com/florian_krammer/status/1377584388179963906?s=20">https://twitter.com/florian_k...
https://twitter.com/ichaydon/status/1377693412065898496?s=20">https://twitter.com/ichaydon/...
Bad news for Sputnik https://twitter.com/macroliter/status/1377988614492188672?s=20">https://twitter.com/macrolite...
https://twitter.com/bhwords/status/1379058843305541639?s=20">https://twitter.com/bhwords/s...
https://twitter.com/MarylouiseMcla1/status/1357107437686300674?s=20">https://twitter.com/Marylouis...
https://twitter.com/CarlosdelRio7/status/1379475995992977413?s=20">https://twitter.com/Carlosdel...
#Servicetweet
This thread is part of the library: https://twitter.com/Boschs_Owl/status/1354390294385586182?s=20">https://twitter.com/Boschs_Ow...
https://twitter.com/SternLab/status/1380922920734711811?s=20">https://twitter.com/SternLab/...
https://twitter.com/nathanheller/status/1380314186949959682?s=20">https://twitter.com/nathanhel...
Nail in the coffin for delaying 2. dose: https://twitter.com/celinegounder/status/1380306862868852737?s=20">https://twitter.com/celinegou...
Why I have come to the conclusion mandatory vaccination is the one and only way out (see previous tweets in this thread, also ECHR ruling): https://twitter.com/jburnmurdoch/status/1380512731456016385?s=20">https://twitter.com/jburnmurd...
#ECHR rules that compulsory vaccination is legal:
https://hudoc.echr.coe.int/app/conversion/pdf/?library=ECHR&id=003-6989051-9414707&filename=Grand%20Chamber%20judgment%20Vavricka%20and%20Others%20v.%20Czech%20Republic%20-%20obligation%20to%20vaccinate%20children%20against%20diseases%20that%20were%20well%20known%20to%20medical%20science.pdf">https://hudoc.echr.coe.int/app/conve...
Finally there are some hints about what happened in the few cases of blood clots after AZ: https://twitter.com/kakape/status/1381208885479026689?s=20">https://twitter.com/kakape/st...
https://twitter.com/toggleModal/status/1380405443592384515?s=20">https://twitter.com/toggleMod...
https://twitter.com/amymaxmen/status/1381273178006122496?s=20">https://twitter.com/amymaxmen...
https://twitter.com/TheBinderLab/status/1381517082643329024?s=20">https://twitter.com/TheBinder...
https://twitter.com/florian_krammer/status/1381928064796528641?s=20">https://twitter.com/florian_k...
AdV‘s and their past https://twitter.com/tskould/status/1381933206358913024?s=20">https://twitter.com/tskould/s...
By @BlnTorsten https://threadreaderapp.com/thread/1385257690935533570.html">https://threadreaderapp.com/thread/13...
Thread by @BlnTorsten on Thread Reader App

Thread by @BlnTorsten: Covid 19 Impfung - und was ich daran wirklich nicht verstehe: - Für uns Reisende war eine Impfplicht (!) in Ländern wie Afrika oder Südamerika völlig normal und bisher kein...

https://threadreaderapp.com/thread/1385257690935533570.html
https://twitter.com/florian_krammer/status/1386964482035965952?s=20">https://twitter.com/florian_k...
I guess this paper will, when published, be noted in medical history books as it shows real-life experience w/ the mRNA vaccines and is •highly comparable• to the studies by Pfizer/BioNTech and Moderna: https://www.medrxiv.org/content/10.1101/2021.04.21.21255873v1.full-text">https://www.medrxiv.org/content/1...
Real World Effectiveness of COVID-19 mRNA Vaccines against Hospitalizations and Deaths in the...

Background Covid-19 has caused significant global mortality. Multiple vaccines have demonstrated efficacy in clinical trials though real-world effectiveness of vaccines against Covid-19 mortality in...

https://www.medrxiv.org/content/10.1101/2021.04.21.21255873v1.full-text
Early work on HAd5 based vaccine targeting the nucleocapsid proteine (currently most target S (spike, includes RBD receptor binding domain). Interesting.
Via @Vineet_Joag https://www.biorxiv.org/content/10.1101/2021.04.26.441518v1">https://www.biorxiv.org/content/1...
Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing antibodies target the receptor binding domain of the spike (S) protein, a focus of...

https://www.biorxiv.org/content/10.1101/2021.04.26.441518v1
#Servicetweet

This is a section of https://twitter.com/Boschs_Owl/status/1388449942239383554?s=20">https://twitter.com/Boschs_Ow...
https://twitter.com/aslavitt46/status/1386753398758838272?s=20">https://twitter.com/aslavitt4...
You can follow @Boschs_Owl.
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