Just published (open access)... our in-depth analysis of on-site monitoring findings from the @MRCCTU @CR_UK @The_MRC #TEMPER study, showing that most of them might be dealt with without a site visit @CarolineHur1 @VickiYE @ClinTrialsJ https://journals.sagepub.com/doi/full/10.1177/1740774520972650 1/n

In particular our work lends support to central monitoring of informed consent forms - many may do this already. Obvious benefits include a) finding problems sooner (pre-randomisation, even) and b) freeing up on-site time for other activities 2/n

Remote access to electronic health records could help but wasn't considered feasible when we asked about it in 2018. Current discussions on implementing remote monitoring (while site visits still not doable) suggest we may not have made much progress with this. Will we ever? 3/n

Still more to be done in growing the evidence-base around monitoring in #clinicaltrials particularly to reduce costs while still protecting participant safety and trial integrity. Looking forward to what others may do about this next... @UKCTUNetwork @MRCNIHRTMRP @mattsydes 4/4