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Fluvoxamine
(auf deutsch: Fluvoxamin)
(It MIGHT help with prophylaxis and/ or treatment of Covid-19 and might lessen the severity of the disease, but remember: this is not medical advice!, check everything & talk to your doctor before believing anything!)
(auf deutsch: Fluvoxamin)
(It MIGHT help with prophylaxis and/ or treatment of Covid-19 and might lessen the severity of the disease, but remember: this is not medical advice!, check everything & talk to your doctor before believing anything!)
Fluvoxamin ist ein auf die Psyche wirkender Stoff, der verhindert, dass der an den Nervenenden freigesetzte Botenstoff Serotonin wieder in die Nervenzelle aufgenommen und dadurch unwirksam gemacht wird.
So steht dem Gehirn mehr von diesem Botenstoff zur Verfügung.
So steht dem Gehirn mehr von diesem Botenstoff zur Verfügung.
Diesen Effekt hat eine ganze Gruppe von Wirkstoffen, die aufgrund ihres Wirkmechanismus SSRI (engl.: selective serotonin re-uptake inhibitor, deutsch: selektive Serotonin-Wiederaufnahme-Hemmer) genannt werden.
deutscher Wikipediaeintrag für das Antidepressivum Fluvoxamin:
https://de.wikipedia.org/wiki/Fluvoxamin
Fluvoxamin bei http://doccheck.com : https://flexikon.doccheck.com/de/Fluvoxamin
https://de.wikipedia.org/wiki/Fluvoxamin
Fluvoxamin bei http://doccheck.com : https://flexikon.doccheck.com/de/Fluvoxamin
english Wikipedia entry for FIASMA:
https://en.wikipedia.org/wiki/FIASMA
english Wikipedia entry for Fluvoxamine:
https://en.wikipedia.org/wiki/Fluvoxamine
https://en.wikipedia.org/wiki/FIASMA
english Wikipedia entry for Fluvoxamine:
https://en.wikipedia.org/wiki/Fluvoxamine
Fluvoxamine is acting as a FIASMA.
FIASMA:
1/2:
Functional inhibitors of acid sphingomyelinase, or FIASMA, is a large group of pharmacological compounds inhibiting the enzyme acid sphingomyelinase.
FIASMA:
1/2:
Functional inhibitors of acid sphingomyelinase, or FIASMA, is a large group of pharmacological compounds inhibiting the enzyme acid sphingomyelinase.
2/2:
It is located within the lysosome, where it cleaves sphingomyelin to ceramide and sphingosine, the latter of which is then phosphorylated to sphingosine-1-phosphate. These metabolites, and the subsequent inhibition, influence the balance between cell death and cell growth.
It is located within the lysosome, where it cleaves sphingomyelin to ceramide and sphingosine, the latter of which is then phosphorylated to sphingosine-1-phosphate. These metabolites, and the subsequent inhibition, influence the balance between cell death and cell growth.
Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19.
A Randomized Clinical Trial
Published on November 12, 2020
Study:
https://jamanetwork.com/journals/jama/fullarticle/2773108
Interpretation 1:
https://twitter.com/farid__jalali/status/1326932053993009152
Interpretation 2: https://twitter.com/Covid19Crusher/status/1326962083301367813
A Randomized Clinical Trial
Published on November 12, 2020
Study:
https://jamanetwork.com/journals/jama/fullarticle/2773108
Interpretation 1:
https://twitter.com/farid__jalali/status/1326932053993009152
Interpretation 2: https://twitter.com/Covid19Crusher/status/1326962083301367813
Fluvoxamine is sold under the brand name Luvox (among others).
discussion of antiviral properties of acid sphingomyelinase inhibitors, Part 1/2: https://twitter.com/__ice9/status/1328719481770815489
discussion of antiviral properties of acid sphingomyelinase inhibitors, Part 2/2:
Quote: "Fluvoxamine and fluoxetine have shown clinical benefit at ordinary doses." https://twitter.com/__ice9/status/1328735304027676672
Quote: "Fluvoxamine and fluoxetine have shown clinical benefit at ordinary doses." https://twitter.com/__ice9/status/1328735304027676672
