The 300-year history of vaccines as app updates:

~1720

v0.1 (beta): Inoculation

Features:
• Grants immunity
• Usually doesn't kill you

Known bugs:
• Mild disease symptoms
• You're still contagious and can start an outbreak

Supported platforms:
• Smallpox

1796

v1.0: Vaccination! Using new cowpox-based technology

Fixed:
• Doesn't kill you or start outbreaks
• Milder symptoms

Bugs:
• Immunity is temporary (booster shot upgrade packs required)

Supported:
• *Still* only smallpox

1885

v2.0: Attenuated/inactivated vaccines. Sorry this one took so long, folks! Had to discover microbiology first. Big shout-out to our lead dev, Pasteur.

Features:
• Rabies support! More diseases coming soon

Bugs:
• Can cause disease if attenuation/inactivation goes wrong

1896, v2.1: Typhoid & cholera support
1897, v2.2: Plague
1932, v2.3: Diphtheria
1926, v2.4: Pertussis (whooping cough)
1927, v2.5: Tetanus, tuberculosis
1945, v2.6: Influenza
1953, v2.7: Yellow fever
1955, v2.8: Polio
1963, v2.9: Measles
1967, v2.10: Mumps
1969, v2.11: Rubella
…

1981

v3.0: Subunit vaccines! Next-gen technology uses only a part of the pathogen.

Features:
• Cannot replicate in the body or cause disease

Supported:
• Hepatitis B
• HPV, meningococcal, pneumococcal, and others coming soon

2020

v4.0: RNA vaccines. Our most advanced vaccine technology yet, featuring personalized and locally-sourced biologics: your own cells produce the antigen!

Supported:
• COVID-19 (private beta)
• Many more sure to come in the future.

A much more serious and informative version of this at @rootsofprogress: https://rootsofprogress.org/immunization-from-inoculation-to-rna-vaccines