1/3 Interesting data from @guptalabunc lab on cellular radioresistance mediated by TP53 which accelerates DNA-PK dependent DSB repair.
#ASTRO20
#radbio
1/3 Interesting data from @guptalabunc lab on cellular radioresistance mediated by TP53 which accelerates DNA-PK dependent DSB repair. #ASTRO20 #radbio
1/3 Interesting data from @guptalabunc lab on cellular radioresistance mediated by TP53 which accelerates DNA-PK dependent DSB repair. #ASTRO20 #radbio
1/3 Interesting data from @guptalabunc lab on cellular radioresistance mediated by TP53 which accelerates DNA-PK dependent DSB repair. #ASTRO20 #radbio
1/3 Interesting data from @guptalabunc lab on cellular radioresistance mediated by TP53 which accelerates DNA-PK dependent DSB repair. #ASTRO20 #radbio
2/3 @guptalabunc reporting elegant cell based analyses to understand p53 dependent DSB repair kinetics and identify backup repair pathways in p53 deficient cells.

p53 and radioresistance is complicated eg
https://pubmed.ncbi.nlm.nih.gov/15197326/ 
https://pubmed.ncbi.nlm.nih.gov/15197326/... href=" https://pubmed.ncbi.nlm.nih.gov/15688024/ 

https://pubmed.ncbi.nlm.nih.gov/15688024/... href="https://twtext.com//hashtag/ASTRO20"> #ASTRO20
#radbio
2/3 @guptalabunc reporting elegant cell based analyses to understand p53 dependent DSB repair kinetics and identify backup repair pathways in p53 deficient cells.p53 and radioresistance is complicated eg https://pubmed.ncbi.nlm.nih.gov/15197326/... href=
2/3 @guptalabunc reporting elegant cell based analyses to understand p53 dependent DSB repair kinetics and identify backup repair pathways in p53 deficient cells.p53 and radioresistance is complicated eg https://pubmed.ncbi.nlm.nih.gov/15197326/... href=
2/3 @guptalabunc reporting elegant cell based analyses to understand p53 dependent DSB repair kinetics and identify backup repair pathways in p53 deficient cells.p53 and radioresistance is complicated eg https://pubmed.ncbi.nlm.nih.gov/15197326/... href=
2/3 @guptalabunc reporting elegant cell based analyses to understand p53 dependent DSB repair kinetics and identify backup repair pathways in p53 deficient cells.p53 and radioresistance is complicated eg https://pubmed.ncbi.nlm.nih.gov/15197326/... href=
3/3 I am curious if TP53 will pan out as predictor of radioresistance in the clinic. Complicated protein, not all mutations are equal & by itself it may have more prognostic rather than predictive value in patients treated with #radiotherapy
Wonder what others think?
#ASTRO20
3/3 I am curious if TP53 will pan out as predictor of radioresistance in the clinic. Complicated protein, not all mutations are equal & by itself it may have more prognostic rather than predictive value in patients treated with #radiotherapy Wonder what others think? #ASTRO20
3/3 I am curious if TP53 will pan out as predictor of radioresistance in the clinic. Complicated protein, not all mutations are equal & by itself it may have more prognostic rather than predictive value in patients treated with #radiotherapy Wonder what others think? #ASTRO20
3/3 I am curious if TP53 will pan out as predictor of radioresistance in the clinic. Complicated protein, not all mutations are equal & by itself it may have more prognostic rather than predictive value in patients treated with #radiotherapy Wonder what others think? #ASTRO20
I need that Twitter edit function, or less distractionshttps://abs.twimg.com/emoji/v2/... draggable="false" alt="😅" title="Lächelndes Gesicht mit offenem Mund und Angstschweiß" aria-label="Emoji: Lächelndes Gesicht mit offenem Mund und Angstschweiß">
This is meant to read that TP53 loss accelerates DSB repair !!
sorry @guptalabunc
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