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"Sleep Disorders - Circadian Rhythms for the Chest Clinician: It& #39;s About Time" starting in less than 5 minutes! Join NOW! #CHEST2020 #CHESTSoMe @accpchest
How fast is your cellular clock ticking? Genetic components of the Mamalian Systems
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
Circadian Dysfunction is also related to Internal synchronization cycles between all our various organ systems! @PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
And the answer is .................................... watch the video! Or join us live right now!!
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
Broad implications of Circadian Disturbance!
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
"Drug the clock and Clock the Drug" - @PhyllisZee
@PhyllisZee #CHEST2020 #CHESTSoMe @accpchest
"Drug the clock and Clock the Drug" - @PhyllisZee
Nocturnal Asthma - some things have been known since the 5th century!
@g_mak #CHEST2020 #CHESTSoMe @accpchest
@g_mak #CHEST2020 #CHESTSoMe @accpchest
Similar studies have been conducted in bacterial PNA, viral PNA and now there are newer studies starting in COVID-19!
@g_mak #CHEST2020 #CHESTSoMe @accpchest
@g_mak #CHEST2020 #CHESTSoMe @accpchest
Interplay in Sleep Disruption, Delirium and Circadian Rhythm!
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
Light, meals, social cues, exercise, ... can all impact Circadian rhythm in the ICU
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
Mind-blowing: Melatonin secretions are rapidly disrupted within one day of ICU stay!!
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
@PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
Delirium associated with disruption in melatonin secretion! @PisaniMAP #CHEST2020 #CHESTSoMe @accpchest
"Shift work is carcinogenic" 
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@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
There are multiple mechanisms linking the disruption of circadian rhythm and tumor growth
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
What can we do about it?
- Chronotherapy
- Target clock genes
- And more!
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
- Chronotherapy
- Target clock genes
- And more!
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
Chronorehabilitation can help restore Circadian Rhythm
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
@DiwakarB1988 #CHEST2020 #CHESTSoMe @accpchest
Melatonin dosing:
Low dose: 0.5mg
Right time: Early evening, NOT at bedtime
Thank you to all the presenters: @PhyllisZee @g_mak @PisaniMAP @DiwakarB1988
Thank you to moderator @gretchemaben
This was an extremely informative for me! Thank you #CHEST2020 #CHESTSoMe @accpchest
Low dose: 0.5mg
Right time: Early evening, NOT at bedtime
Thank you to all the presenters: @PhyllisZee @g_mak @PisaniMAP @DiwakarB1988
Thank you to moderator @gretchemaben
This was an extremely informative for me! Thank you #CHEST2020 #CHESTSoMe @accpchest
