Since everyone is suddenly VERY INTERESTED in steroid side effects 🙃, here is a 🧵 of the ones that your preceptors would likely expect you to be aware of as a #pharmacystudent.

1/11
🧠 + 💤: Mood and sleep disturbances. Sometimes psychosis, which is getting all the attention rn, but minor changes - like irritability - are more common.

♥️: Hypertension as a long-term side effect. Hypotension as a short-term side effect during / immediately after an IV dose.
🦠: Immunosuppression / increased risk of infection / altered response to vaccines.

It’s a topic worthy of a 🧵 of its own, but 🔑 for #pharmacystudents on a #PedsPharm rotation is to double-check ✔️ CDC guidance on vaccine schedules 💉 📆 and steroids.

3/11
❗️: Hypothalamic-pituitary-adrenal (HPA) suppression.

Another topic worthy of its own 🧵, but 🔑 for #pharmacystudents is to remember steroid tapers are as much art 🎨 as science 🧪, so go ahead and calculate ➗✖️ the “ideal” regimen, but then ROUND IT to something measurable.
💪🏽: Myopathy.

🦴: Osteopenia / osteoporosis as a long-term side effect.

In the peds lupus clinic, bone health is the most common topic Grace and I review with patients! We talk about weight-bearing exercise 🏋🏾‍♀️, calcium-rich foods / calcium supplements 🥛, and vitamin D ☀️.
👁: Blurred vision, cataracts, glaucoma.

🍭: Impaired glucose metabolism, insulin resistance, beta cell dysfunction.

💧: Fluid retention, edema.

6/11
🤢: GI upset, or worse, gastric ulcers. Concomitant NSAIDs may increase the risk, and H2 antagonists are sometimes added as a protective measure. ( #TwitteRx could probably have a very long, heated debate about this topic... )

7/11
🧴: I’m intentionally not talking about topical steroids in detail, because there is already a great 🧵 out there, but!!!

An ADE + counseling point that I often see #pharmacystudents forget: Steroids cause thinning of the skin. Apply as a THIN layer. https://twitter.com/drsteventchen/status/1123605778127052800?s=21
⚪️ Leukocytosis. There’s an interesting 🧵 here: https://twitter.com/tony_breu/status/1053671032140251136?s=21
And if you’re a #pharmacyresident on a #specialtypharmacy learning experience, you might want to know more about steroids and eosinophils specifically. There’s an amazing 🧵 here: https://twitter.com/avrahamcoopermd/status/1304825763984703489?s=21
#TwitteRx please chime in 🛎 if I missed something super interesting or specific to a certain patient population!

And quick study tips:
🖍 Draw a stick figure and write in ADEs over corresponding body parts / organ systems.
🦶🏻Listing them head to toe used to help me!

11/11
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