Our latest paper is now published online with @AmJGastro
https://journals.lww.com/ajg/Abstract/9000/Symptom_Stability_in_Rome_IV_vs_Rome_III_Irritable.99117.aspx

In it we examined symptom stability according to the Rome IV or Rome III criteria in >700 people with IBS.
What did we find?
1⃣ During 12 months of follow-up, fluctuation of symptoms of IBS to another functional bowel disorder occurred in 17% to 30% of people, but was highest using the Rome IV criteria.
During 12 months of follow-up, fluctuation of symptoms of IBS to another functional bowel disorder occurred in 17% to 30% of people, but was highest using the Rome IV criteria.
During 12 months of follow-up, fluctuation of symptoms of IBS to another functional bowel disorder occurred in 17% to 30% of people, but was highest using the Rome IV criteria.
2⃣ Among those who still met criteria for IBS, between 25% and 32% fluctuated according to their predominant stool subtype, but again this was highest using the Rome IV criteria. IBS-M was the most stable subtype with Rome III, but the least stable with Rome IV.
Among those who still met criteria for IBS, between 25% and 32% fluctuated according to their predominant stool subtype, but again this was highest using the Rome IV criteria. IBS-M was the most stable subtype with Rome III, but the least stable with Rome IV.
Among those who still met criteria for IBS, between 25% and 32% fluctuated according to their predominant stool subtype, but again this was highest using the Rome IV criteria. IBS-M was the most stable subtype with Rome III, but the least stable with Rome IV.
3⃣ New treatments commenced during follow-up were recorded. Fluctuation of predominant stool subtype did not appear to be related to commencing a new treatment.
New treatments commenced during follow-up were recorded. Fluctuation of predominant stool subtype did not appear to be related to commencing a new treatment.
New treatments commenced during follow-up were recorded. Fluctuation of predominant stool subtype did not appear to be related to commencing a new treatment.
New treatments commenced during follow-up were recorded. Fluctuation of predominant stool subtype did not appear to be related to commencing a new treatment.
New treatments commenced during follow-up were recorded. Fluctuation of predominant stool subtype did not appear to be related to commencing a new treatment.
4⃣ Using stool type to subgroup patients to direct therapy is problematic. Other approaches to subgrouping people with IBS, which take account of the complex and multi-faceted nature of the disorder may be preferable. More data from our group will be coming on this subject…
@bribarberio @DrCJBlack @Lesley10882267 @constipationyan and Edoardo Savarino
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